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Details on Person MTMR4 attenuates transforming growth factor beta (TGFbeta) signaling by dephosphorylating R-Smads in endosomes

Class:IdLiteratureReference:2187402
_displayNameMTMR4 attenuates transforming growth factor beta (TGFbeta) signaling by dephosphorylating R-Smads in endosomes
_timestamp2012-04-09 20:48:42
author[Person:2176463] Yu, J
[Person:2187398] Pan, L
[Person:2187409] Qin, X
[Person:2187408] Chen, H
[Person:2187407] Xu, Y
[Person:2187366] Chen, Y
[Person:2187397] Tang, H
created[InstanceEdit:2187403] Orlic-Milacic, M, 2012-04-09
journalJ Biol Chem
pages8454-62
pubMedIdentifier20061380
titleMTMR4 attenuates transforming growth factor beta (TGFbeta) signaling by dephosphorylating R-Smads in endosomes
volume285
year2010
(literatureReference)[Pathway:2173788] Downregulation of TGF-beta receptor signaling [Homo sapiens]
[Reaction:2187401] MTMR4 dephosphorylates SMAD2/3 [Homo sapiens]
[Reaction:2187405] MTMR4 binds phosphorylated SMAD2/3 [Homo sapiens]
[Pathway:9846195] GOCAM Downregulation of TGF-beta receptor signaling [Homo sapiens]
[Reaction:9846253] GOCAM MTMR4 binds phosphorylated SMAD2/3 [Homo sapiens]
[Reaction:9846254] GOCAM MTMR4 dephosphorylates SMAD2/3 [Homo sapiens]
[Summation:2187400] A protein phosphatase MTMR4, residing in the early endosome ...
[Summation:2187406] MTMR4 protein phosphatase dephosphorylates SMAD2 and SMAD3, ...
[Summation:2190603] TGF-beta receptor signaling is downregulated by proteasome a...
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