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Details on Person Platelet glycoprotein 4 binds ligands

Class:Id	Reaction:2187263
_displayName	Platelet glycoprotein 4 binds ligands
_doRelease	TRUE
_timestamp	2014-02-06 22:14:35
authored	[InstanceEdit:2173787] May, B, 2012-04-02
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:2187262] May, B, 2012-04-07
edited	[InstanceEdit:2173787] May, B, 2012-04-02
input	[EntityWithAccessionedSequence:2187219] Cd36 [plasma membrane] [Mus musculus] [DefinedSet:2187236] Ligands of Cd36 [extracellular region] [Mus musculus]
isChimeric	FALSE
literatureReference	[LiteratureReference:2187084] Adipocytes recognize and degrade oxidized low density lipoprotein through CD36 [LiteratureReference:2187087] CD36 is a receptor for oxidized low density lipoprotein [LiteratureReference:2187095] CD36 is a sensor of diacylglycerides [LiteratureReference:2187132] Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species [LiteratureReference:2187147] Oxidized phosphatidylserine-CD36 interactions play an essential role in macrophage-dependent phagocytosis of apoptotic cells [LiteratureReference:2187154] Phosphocholine as a pattern recognition ligand for CD36 [LiteratureReference:2187156] Receptors for oxidized low-density lipoprotein on elicited mouse peritoneal macrophages can recognize both the modified lipid moieties and the modified protein moieties: implications with respect to macrophage recognition of apoptotic cells [LiteratureReference:2187189] Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages [LiteratureReference:2187196] The binding of oxidized low density lipoprotein to mouse CD36 is mediated in part by oxidized phospholipids that are associated with both the lipid and protein moieties of the lipoprotein
modified	[InstanceEdit:2203481] May, B, 2012-04-22 [InstanceEdit:2213042] May, B, 2012-04-28 [InstanceEdit:3108241] May, B, 2013-02-10 [InstanceEdit:3166793] May, B, 2013-02-23 [InstanceEdit:3222523] May, B, 2013-03-22 [InstanceEdit:5258170] May, B, 2014-02-06 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Platelet glycoprotein 4 binds ligands
output	[Complex:2187248] Platelet glycoprotein 4: Ligand [plasma membrane] [Mus musculus]
releaseDate	2013-06-11
reviewed	[InstanceEdit:3222522] Neyen, Claudine, 2013-03-22
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:3654436] R-MMU-2187263.2
summation	[Summation:2213034] Cd36 (Platelet glycoprotein IV) binds oxidized LDL, beta-glu...
(inferredFrom)	[Reaction:2187264] Platelet glycoprotein IV (CD36) binds ligands [Homo sapiens]
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No pathways have been reviewed or authored by Platelet glycoprotein 4 binds ligands (2187263)