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Details on Person NEDD4L ubiquitinates nuclear SMAD2 and SMAD3 phosphorylated ...

Class:IdSummation:2176501
_displayNameNEDD4L ubiquitinates nuclear SMAD2 and SMAD3 phosphorylated ...
_timestamp2012-04-13 18:26:14
created[InstanceEdit:2176500] Orlic-Milacic, M, 2012-04-02
literatureReference[LiteratureReference:2176494] Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling
modified[InstanceEdit:2197664] Orlic-Milacic, M, 2012-04-13
textNEDD4L ubiquitinates nuclear SMAD2 and SMAD3 phosphorylated at the linker region by CDK8 or CDK9, targeting SMAD2 and SMAD3 for degradation.
(summation)[Reaction:2176502] NEDD4L ubiquitinates SMAD2/3 [Homo sapiens]
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