Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person MSR1 (SCARA1, SR-A) binds ligands

Class:Id	Reaction:2173778
_displayName	MSR1 (SCARA1, SR-A) binds ligands
_doRelease	TRUE
_timestamp	2014-02-06 22:14:20
authored	[InstanceEdit:3222522] Neyen, Claudine, 2013-03-22 [InstanceEdit:3000476] May, B, 2013-01-26
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:2173777] May, B, 2012-04-02
edited	[InstanceEdit:2168898] May, B, 2012-03-25
inferredFrom	[Reaction:2173779] Msr1 (Scara1) Binds Ligands [Mus musculus]
input	[DefinedSet:2173760] Ligands of MSR1 [extracellular region] [Homo sapiens] [Complex:2173771] MSR1 (SCARA1) trimer [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:2173624] Role of lysines in mediating interaction of modified low density lipoproteins with the scavenger receptor of human monocyte macrophages [LiteratureReference:2173687] An accessory to the 'Trinity': SR-As are essential pathogen sensors of extracellular dsRNA, mediating entry and leading to subsequent type I IFN responses [LiteratureReference:2173668] Effect of overexpression of human SR-AI on oxLDL uptake and apoptosis in 293T cells [LiteratureReference:2173686] A naturally occurring isoform of the human macrophage scavenger receptor (SR-A) gene generated by alternative splicing blocks modified LDL uptake [LiteratureReference:2299661] Scavenger receptor class-A is a novel cell surface receptor for double-stranded RNA [LiteratureReference:3221707] The scavenger cell pathway for lipoprotein degradation: specificity of the binding site that mediates the uptake of negatively-charged LDL by macrophages [LiteratureReference:3221718] Macrophage scavenger receptor A mediates adhesion to apolipoproteins A-I and E [LiteratureReference:3221721] Endocytic uptake of lysophosphatidylcholine mediated by macrophage scavenger receptor plays a major role in oxidized low density lipoprotein-induced macrophage growth [LiteratureReference:3221700] Scavenger receptor-mediated uptake and metabolism of lipid vesicles containing acidic phospholipids by mouse peritoneal macrophages [LiteratureReference:3221769] Scavenger receptors mediate adhesion of activated B lymphocytes [LiteratureReference:3221791] Scavenger receptor-A mediates gp96/GRP94 and calreticulin internalization by antigen-presenting cells [LiteratureReference:3221644] Identification of Neisseria meningitidis nonlipopolysaccharide ligands for class A macrophage scavenger receptor by using a novel assay [LiteratureReference:2213039] Recognition and plasma clearance of endotoxin by scavenger receptors [LiteratureReference:3221626] The type I macrophage scavenger receptor binds to gram-positive bacteria and recognizes lipoteichoic acid [LiteratureReference:3221820] Scavenger receptor A: a new route for adenovirus 5 [LiteratureReference:3221658] Molecular flypaper, atherosclerosis, and host defense: structure and function of the macrophage scavenger receptor [LiteratureReference:3221698] The class A scavenger receptor binds to proteoglycans and mediates adhesion of macrophages to the extracellular matrix [LiteratureReference:3221655] Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils [LiteratureReference:3221808] Macrophage scavenger receptor mediates the endocytic uptake and degradation of advanced glycation end products of the Maillard reaction [LiteratureReference:3221817] Polynucleotide binding to macrophage scavenger receptors depends on the formation of base-quartet-stabilized four-stranded helices [LiteratureReference:3221804] Binding studies of a triple-helical peptide model of macrophage scavenger receptor to tetraplex nucleic acids [LiteratureReference:3221622] Recognition of solubilized apoproteins from delipidated, oxidized low density lipoprotein (LDL) by the acetyl-LDL receptor [LiteratureReference:3221612] Evidence that the lipid moiety of oxidized low density lipoprotein plays a role in its interaction with macrophage receptors [LiteratureReference:3221662] Selective adhesion of macrophages to denatured forms of type I collagen is mediated by scavenger receptors
modified	[InstanceEdit:2187259] May, B, 2012-04-07 [InstanceEdit:2203481] May, B, 2012-04-22 [InstanceEdit:2213042] May, B, 2012-04-28 [InstanceEdit:2299676] May, B, 2012-06-01 [InstanceEdit:2512885] May, B, 2012-10-08 [InstanceEdit:2528976] May, B, 2012-10-14 [InstanceEdit:3108241] May, B, 2013-02-10 [InstanceEdit:3166793] May, B, 2013-02-23 [InstanceEdit:3221842] May, B, 2013-03-17 [InstanceEdit:3222523] May, B, 2013-03-22 [InstanceEdit:3465590] May, B, 2013-05-17 [InstanceEdit:5258170] May, B, 2014-02-06 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	MSR1 (SCARA1, SR-A) binds ligands
output	[Complex:2173774] MSR1:Ligand [plasma membrane] [Homo sapiens]
releaseDate	2013-06-11
reviewed	[InstanceEdit:3222522] Neyen, Claudine, 2013-03-22
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:3654189] R-HSA-2173778.2
summation	[Summation:2186964] MSR1 (SCARA1, SR-A) binds oxidized and acetylated low densit...
(hasEvent)	[Pathway:3000480] Scavenging by Class A Receptors [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:2507854] MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by MSR1 (SCARA1, SR-A) binds ligands (2173778)