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Details on Person Recruitment of PLK1 to phosphorylated GORASP1 (GRASP65)

Class:Id	Reaction:2172194
_displayName	Recruitment of PLK1 to phosphorylated GORASP1 (GRASP65)
_doRelease	TRUE
_timestamp	2017-12-06 21:09:21
authored	[InstanceEdit:2424242] Orlic-Milacic, M, 2012-07-20
compartment	[Compartment:20699] Golgi membrane [Compartment:70101] cytosol
created	[InstanceEdit:2172195] Orlic-Milacic, M, 2012-03-29
edited	[InstanceEdit:2426592] Gillespie, ME, 2012-08-07
inferredFrom	[Reaction:2423781] PLK1 binds phosphorylated Gorasp1 [Homo sapiens]
input	[Complex:2172185] p-T216,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP [Golgi membrane] [Homo sapiens] [EntityWithAccessionedSequence:3000318] p-T210-PLK1 [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:162969] Plk1 docking to GRASP65 phosphorylated by Cdk1 suggests a mechanism for Golgi checkpoint signalling
modified	[InstanceEdit:2311351] Orlic-Milacic, M, 2012-06-06 [InstanceEdit:2423783] Orlic-Milacic, M, 2012-07-19 [InstanceEdit:2426700] Orlic-Milacic, M, 2012-08-08 [InstanceEdit:2457762] Orlic-Milacic, M, 2012-08-28 [InstanceEdit:2463849] Orlic-Milacic, M, 2012-08-30 [InstanceEdit:2463853] Orlic-Milacic, M, 2012-08-30 [InstanceEdit:2466353] Matthews, L, 2012-09-07 [InstanceEdit:2466354] Matthews, L, 2012-09-07 [InstanceEdit:2507814] Orlic-Milacic, M, 2012-10-04 [InstanceEdit:2660809] D'Eustachio, P, 2012-11-23 [InstanceEdit:8982276] Orlic-Milacic, Marija, 2017-03-16 [InstanceEdit:9032153] Orlic-Milacic, Marija, 2017-12-06 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Recruitment of PLK1 to phosphorylated GORASP1 (GRASP65)
output	[Complex:2172193] p-T216,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1 [Golgi membrane] [Homo sapiens]
precedingEvent	[Reaction:3000327] PLK1 phosphorylates BORA [Homo sapiens] [Reaction:3000310] AURKA phosphorylates PLK1 [Homo sapiens] [Reaction:2172183] Phosphorylation of GORASP1, GOLGA2 and RAB1A by CDK1:CCNB [Homo sapiens] [Reaction:170161] Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B [Homo sapiens]
releaseDate	2012-09-18
reviewed	[InstanceEdit:2463852] Wang, Yanzhuang, 2012-08-19 [InstanceEdit:2463846] Colanzi, Antonino, 2012-08-21 [InstanceEdit:2507813] Malhotra, Vivek, 2012-08-15
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2464981] R-HSA-2172194.4
summation	[Summation:2311349] Phosphorylation of GORASP1 (GRASP65) by cyclin B-associated ...
(hasEvent)	[Pathway:162658] Golgi Cisternae Pericentriolar Stack Reorganization [Homo sapiens]
(precedingEvent)	[Reaction:2214351] PLK1 phosphorylates GORASP1 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9781384] Update Tracker - [Reaction:2172194] Recruitment of PLK1 to phosphorylated GORASP1 (GRASP65) - v61:[add_removeInput]
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