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Details on Person Hemopexin binds Hemes

Class:Id	Reaction:2168886
_displayName	Hemopexin binds Hemes
_doRelease	TRUE
_timestamp	2020-12-24 10:47:19
authored	[InstanceEdit:2168858] May, B, 2012-03-21
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:2168882] May, B, 2012-03-25
edited	[InstanceEdit:2168858] May, B, 2012-03-21
input	[EntityWithAccessionedSequence:2168860] HPX [extracellular region] [Homo sapiens] [CandidateSet:9707310] Hemes [extracellular region]
isChimeric	FALSE
literatureReference	[LiteratureReference:2168836] pH- and metal ion-linked stability of the hemopexin-heme complex [LiteratureReference:2168793] The binding and transport of heme by hemopexin [LiteratureReference:2168829] Metal ions and electrolytes regulate the dissociation of heme from human hemopexin at physiological pH [LiteratureReference:2168824] Kinetics of hemin distribution in plasma reveals its role in lipoprotein oxidation [LiteratureReference:2168742] Serum proteins as mediators of hemin efflux from red cell membranes: specificity of hemopexin [LiteratureReference:2168826] Hemin binding to serum proteins and the catalysis of interprotein transfer
modified	[InstanceEdit:2203500] May, B, 2012-04-22 [InstanceEdit:3108241] May, B, 2013-02-10 [InstanceEdit:3145021] May, B, 2013-02-13 [InstanceEdit:3150153] May, B, 2013-02-18 [InstanceEdit:5258170] May, B, 2014-02-06 [InstanceEdit:9710017] Jassal, Bijay, 2020-12-24 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Hemopexin binds Hemes
output	[Complex:2168851] HPX:Hemes [extracellular region] [Homo sapiens]
precedingEvent	[Reaction:9707516] FeHM dissociates from MetHb [Homo sapiens] [Reaction:9707504] H2O2 oxidises ferrohemoglobin to MetHb [Homo sapiens] [Reaction:9707586] FeHM oxidises LDL,HDL [Homo sapiens] [Reaction:9707516] FeHM dissociates from MetHb [Homo sapiens]
releaseDate	2013-03-12
reviewed	[InstanceEdit:3145008] Tolosano, Emanuela, 2013-02-13 [InstanceEdit:3145005] Fiorito, Veronica, 2013-02-13 [InstanceEdit:3150152] Moestrup, S�ren Kragh, 2013-02-18
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:3200253] R-HSA-2168886.3
summation	[Summation:2168890] Hemopexin binds either ferriheme b or ferroheme b, however t...
(hasEvent)	[Pathway:2168880] Scavenging of heme from plasma [Homo sapiens]
(precedingEvent)	[Reaction:2168897] LRP1 (CD91) binds Hemopexin:heme [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9776299] Update Tracker - [Reaction:2168886] Hemopexin binds Hemes - v76:[add_removeInput]
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No pathways have been reviewed or authored by Hemopexin binds Hemes (2168886)