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Details on Person UniProt:Q6KAR6 Exoc3

Class:IdReferenceGeneProduct:216823
_chainChangeLogchain:1-755 added on Fri February 6 2015
_displayNameUniProt:Q6KAR6 Exoc3
_timestamp2023-11-03 16:56:19
chainchain:1-755
checksum47B4D8AFAAC7CBCB
commentFUNCTION Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.SUBUNIT The exocyst complex is composed of EXOC1, EXOC2, EXOC3, EXOC4, EXOC5, EXOC6, EXOC7 and EXOC8 (By similarity). Interacts with EXOC3L1 (PubMed:18480549). Interacts with BIRC6/bruce (By similarity). Interacts with MYRIP (PubMed:17827149). Interacts with SLC6A9 (By similarity).SUBCELLULAR LOCATION Perinuclear in undifferentiated cells. Redistributes to growing neurites and growth cones during neuronal differentiation (By similarity). During mitosis, early recruitment to the midbody requires RALA, but not RALB, and EXOC2. In late stages of cytokinesis, localization to the midbody is RALB-dependent (By similarity).SIMILARITY Belongs to the SEC6 family.CAUTION It is uncertain whether Met-1 or Met-11 is the initiator.SEQUENCE CAUTION Extended N-terminus.
created[InstanceEdit:216819] May, B, 2008-03-23 13:50:41
descriptionrecommendedName: Exocyst complex component 3 alternativeName: Exocyst complex component Sec6
geneNameExoc3
Sec6l1
identifierQ6KAR6
isSequenceChangedFALSE
keywordAcetylation
Cell projection
Cytoplasm
Exocytosis
Golgi apparatus
Protein transport
Reference proteome
Transport
modified[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
[InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12
[InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39
[InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18
[InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35
[InstanceEdit:423310] Kanapin, AA
[InstanceEdit:435478] Kanapin, AA
[InstanceEdit:435871] Kanapin, AA
[InstanceEdit:447347] Kanapin, AA
[InstanceEdit:525883] Kanapin, AA
[InstanceEdit:613449] Kanapin, AA
[InstanceEdit:797602] Kanapin, AA
[InstanceEdit:937368] Yung, CK
[InstanceEdit:1042053] Yung, CK
[InstanceEdit:1220657] Yung, CK
[InstanceEdit:1300696] Yung, CK
[InstanceEdit:1301627] Yung, CK
[InstanceEdit:1551960] Weiser, JD
[InstanceEdit:1995863] Weiser, JD
[InstanceEdit:2132304] Weiser, JD
[InstanceEdit:2265580] Weiser, JD
[InstanceEdit:5433710] Weiser, JD
[InstanceEdit:5618415] Weiser, JD
[InstanceEdit:5634237] Weiser, JD
[InstanceEdit:5673015] Weiser, JD
[InstanceEdit:9015733] Weiser, JD
[InstanceEdit:9037114] Weiser, JD
[InstanceEdit:9637257] Weiser, JD
[InstanceEdit:9645038] Weiser, JD
[InstanceEdit:9676415] Weiser, JD
[InstanceEdit:9796772] Weiser, Joel
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
nameExoc3
referenceDatabase[ReferenceDatabase:2] UniProt
secondaryIdentifierEXOC3_MOUSE
sequenceLength755
species[Species:48892] Mus musculus
(referenceEntity)[EntityWithAccessionedSequence:216824] EXOC3 (Sec6) (in mature granule membrane) [secretory granule membrane] [Mus musculus]
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No pathways have been reviewed or authored by UniProt:Q6KAR6 Exoc3 (216823)