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Details on Person The substrate of Greatwall kinase, Arpp19, controls mitosis by inhibiting protein phosphatase 2A

Class:IdLiteratureReference:2168075
_displayNameThe substrate of Greatwall kinase, Arpp19, controls mitosis by inhibiting protein phosphatase 2A
_timestamp2012-03-23 16:56:01
author[Person:2168070] Gharbi-Ayachi, A
[Person:174114] Labbe, JC
[Person:2168074] Burgess, Andrew
[Person:174187] Vigneron, S
[Person:157786] Strub, JM
[Person:2168067] Brioudes, E
[Person:2168072] Van-Dorsselaer, A
[Person:174103] Castro, A
[Person:170233] Lorca, T
created[InstanceEdit:2168071] Orlic-Milacic, M, 2012-03-23
journalScience
modified[InstanceEdit:2168077] Orlic-Milacic, M, 2012-03-23
pages1673-7
pubMedIdentifier21164014
titleThe substrate of Greatwall kinase, Arpp19, controls mitosis by inhibiting protein phosphatase 2A
volume330
year2010
(literatureReference)[Reaction:2168079] MASTL (GWL) phosphorylates ARPP19 [Homo sapiens]
[Reaction:2430535] MASTL phosphorylates ENSA [Homo sapiens]
[Reaction:2430552] p-S62-ARPP19/p-S67-ENSA binds PP2A-PPP2R2D [Homo sapiens]
[Reaction:2445086] p-S67-Ensa/p-S67-Arpp19 binds PP2A-Ppp2r2d [Xenopus laevis]
[Pathway:2465910] MASTL Facilitates Mitotic Progression [Homo sapiens]
[Summation:2168069] At mitotic entry, phosphorylated MASTL (GWL i.e. great wall ...
[Summation:2168080] MASTL (GWL i.e. Greatwall kinase) phosphorylates ARPP19 on s...
[Summation:2430560] MASTL (GWL) activates ENSA by phosphorylating it on serine r...
[Summation:2430562] ARPP19 and ENSA, activated by MASTL (GWL) mediated phosphory...
[Summation:2445087] Recombinant Xenopus Ensa and Arpp19 are phosphorylated by re...
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