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Details on Person The substrate of Greatwall kinase, Arpp19, controls mitosis by inhibiting protein phosphatase 2A
| Class:Id | LiteratureReference:2168075 |
| _displayName | The substrate of Greatwall kinase, Arpp19, controls mitosis by inhibiting protein phosphatase 2A |
| _timestamp | 2012-03-23 16:56:01 |
| author | [Person:2168070] Gharbi-Ayachi, A [Person:174114] Labbe, JC [Person:2168074] Burgess, Andrew [Person:174187] Vigneron, S [Person:157786] Strub, JM [Person:2168067] Brioudes, E [Person:2168072] Van-Dorsselaer, A [Person:174103] Castro, A [Person:170233] Lorca, T |
| created | [InstanceEdit:2168071] Orlic-Milacic, M, 2012-03-23 |
| journal | Science |
| modified | [InstanceEdit:2168077] Orlic-Milacic, M, 2012-03-23 |
| pages | 1673-7 |
| pubMedIdentifier | 21164014 |
| title | The substrate of Greatwall kinase, Arpp19, controls mitosis by inhibiting protein phosphatase 2A |
| volume | 330 |
| year | 2010 |
| (literatureReference) | [Reaction:2168079] MASTL (GWL) phosphorylates ARPP19 [Homo sapiens] [Reaction:2430535] MASTL phosphorylates ENSA [Homo sapiens] [Reaction:2430552] p-S62-ARPP19/p-S67-ENSA binds PP2A-PPP2R2D [Homo sapiens] [Reaction:2445086] p-S67-Ensa/p-S67-Arpp19 binds PP2A-Ppp2r2d [Xenopus laevis] [Pathway:2465910] MASTL Facilitates Mitotic Progression [Homo sapiens] [Summation:2168069] At mitotic entry, phosphorylated MASTL (GWL i.e. great wall ... [Summation:2168080] MASTL (GWL i.e. Greatwall kinase) phosphorylates ARPP19 on s... [Summation:2430560] MASTL (GWL) activates ENSA by phosphorylating it on serine r... [Summation:2430562] ARPP19 and ENSA, activated by MASTL (GWL) mediated phosphory... [Summation:2445087] Recombinant Xenopus Ensa and Arpp19 are phosphorylated by re... |
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