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Details on Person UniProt:Q8BJM5 Slc30a6
| Class:Id | ReferenceGeneProduct:216780 |
|---|---|
| _chainChangeLog | chain:1-460 added on Fri February 6 2015 |
| _displayName | UniProt:Q8BJM5 Slc30a6 |
| _timestamp | 2023-11-03 16:17:53 |
| chain | chain:1-460 |
| checksum | A3E910CE96D16015 |
| comment | FUNCTION Has probably no intrinsic transporter activity but together with SLC30A5 forms a functional zinc ion:proton antiporter heterodimer, mediating zinc entry into the lumen of organelles along the secretory pathway (Probable). As part of that zinc ion:proton antiporter, contributes to zinc ion homeostasis within the early secretory pathway and regulates the activation and folding of enzymes like alkaline phosphatases and enzymes involved in phosphatidylinositol glycan anchor biosynthesis (By similarity).SUBUNIT Heterodimer with SLC30A5; form a functional zinc ion transmembrane transporter.SUBCELLULAR LOCATION Expressed in brain and liver, and to a lower extent also in lung. Highly expressed in brain (at protein level).SIMILARITY Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.CAUTION Hydrophilic histidine residues that participate to zinc binding in transporters of the family are not conserved in SLC30A6. |
| created | [InstanceEdit:216779] May, B, 2008-03-22 08:23:27 |
| description | recommendedName: Zinc transporter 6 shortName: ZnT-6 alternativeName: Solute carrier family 30 member 6 |
| geneName | Slc30a6 Znt6 |
| identifier | Q8BJM5 |
| isSequenceChanged | FALSE |
| keyword | Golgi apparatus Ion transport Membrane Reference proteome Transmembrane Transmembrane helix Transport Zinc Zinc transport |
| modified | [InstanceEdit:216815] May, B, 2008-03-22 08:36:08 [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53 [InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12 [InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39 [InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18 [InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35 [InstanceEdit:423310] Kanapin, AA [InstanceEdit:435478] Kanapin, AA [InstanceEdit:435871] Kanapin, AA [InstanceEdit:447347] Kanapin, AA [InstanceEdit:525883] Kanapin, AA [InstanceEdit:613449] Kanapin, AA [InstanceEdit:797602] Kanapin, AA [InstanceEdit:937368] Yung, CK [InstanceEdit:1042053] Yung, CK [InstanceEdit:1220657] Yung, CK [InstanceEdit:1300696] Yung, CK [InstanceEdit:1301627] Yung, CK [InstanceEdit:1551960] Weiser, JD [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:3445779] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5618415] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9657908] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9829221] Weiser, Joel [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 |
| name | Slc30a6 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | ZNT6_MOUSE Q3UB35 Q6NVE0 Q8K4H6 Q8R4Z2 Q99JQ3 |
| sequenceLength | 460 |
| species | [Species:48892] Mus musculus |
| (referenceEntity) | [EntityWithAccessionedSequence:216773] Zinc Transporter 6 (ZnT6) [Golgi membrane] [Mus musculus] |
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No pathways have been reviewed or authored by UniProt:Q8BJM5 Slc30a6 (216780)
