Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person Zinc Transporters ZnT5, ZnT6, and ZnT7 are found in the memb...

Class:IdSummation:216774
_displayNameZinc Transporters ZnT5, ZnT6, and ZnT7 are found in the memb...
_timestamp2008-03-29 10:22:39
created[InstanceEdit:216779] May, B, 2008-03-22 08:23:27
modified[InstanceEdit:216815] May, B, 2008-03-22 08:36:08
[InstanceEdit:264202] May, B, 2008-03-29 10:21:39
textZinc Transporters ZnT5, ZnT6, and ZnT7 are found in the membrane of the Golgi in pancreatic cells (and also in many other cell types). They are presumed to play a role in maintaining the high zinc concentration in the Golgi lumen and thus catalyzing the formation of the proinsulin-zinc-calcium complex, which forms spontaneously due to the zinc-binding capability of hexameric proinsulin. Other transporters, such as the newly identified ZnT9 and ZnT10, may also be involved but this is presently unknown.
(summation)[BlackBoxEvent:216660] Formation of Proinsulin-Zinc-Calcium Complex [Mus musculus]
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