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Details on Person Translation of Insulin mRNA

Class:Id	BlackBoxEvent:216672
_displayName	Translation of Insulin mRNA
_timestamp	2016-07-15 23:50:08
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:216671] May, B, 2008-03-19 13:27:02
input	[DefinedSet:216476] Insulin transcripts [cytosol] [Mus musculus]
literatureReference	[LiteratureReference:264281] The role of assembly in insulin's biosynthesis [LiteratureReference:264396] Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis [LiteratureReference:264395] Translational control of proinsulin synthesis by glucose [LiteratureReference:264391] Glucose-induced translational control of proinsulin biosynthesis is proportional to preproinsulin mRNA levels in islet beta-cells but not regulated via a positive feedback of secreted insulin
modified	[InstanceEdit:216890] May, B, 2008-03-24 09:03:11 [InstanceEdit:264235] May, B, 2008-03-29 11:04:45 [InstanceEdit:264390] May, B, 2008-03-30 13:53:45 [InstanceEdit:8879177] Wu, G, 2016-07-15
name	Translation of Insulin mRNA
output	[DefinedSet:216659] Preproinsulin [cytosol] [Mus musculus]
precedingEvent	[BlackBoxEvent:216409] Transcription of Insulin Genes [Mus musculus] [Reaction:216419] Recruitment of RNA polymerase II to Insulin Gene promoter [Mus musculus]
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:8912509] R-MMU-216672.1
summation	[Summation:264211] The translation of mRNAs from Ins-1 and Ins-2 genes is initi...
(hasEvent)	[Pathway:216455] Insulin Synthesis and Secretion [Mus musculus]
(precedingEvent)	[Reaction:216683] Signal Recognition [Mus musculus]
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No pathways have been reviewed or authored by Translation of Insulin mRNA (216672)