Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
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Details on Person CYP3A43 belongs to the cytochrome P450 3A family, of which C...
| Class:Id | Summation:216548 |
|---|---|
| _displayName | CYP3A43 belongs to the cytochrome P450 3A family, of which C... |
| _timestamp | 2014-06-23 14:47:19 |
| created | [InstanceEdit:216615] Jassal, B, 2008-03-18 13:03:19 |
| modified | [InstanceEdit:216640] Jassal, B, 2008-03-18 13:06:36 [InstanceEdit:351808] Jassal, B, 2008-05-28 14:47:12 [InstanceEdit:5602279] Jassal, Bijay, 2014-06-23 |
| text | CYP3A43 belongs to the cytochrome P450 3A family, of which CYP3A4 is the most active member in the biotransformation of xenobiotics. Testosterone (TEST) metabolites are a major determinant of prostate growth and differentiation. CYP3A43, which is expressed in the prostate, exhibits minor 6-beta-hydroxylation activity towards TEST suggesting CYP3A43 may be involved in the etiology of prostate cancer (Domanski et al. 2001, Zeigler-Johnson et al. 2004). |
| (summation) | [Reaction:211959] CYP3A43 6b-hydroxylates TEST [Homo sapiens] |
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No pathways have been reviewed or authored by CYP3A43 belongs to the cytochrome P450 3A family, of which C... (216548)
