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Details on Person 72) Arachidonic acid is epoxidated to 14,15-EET by CYP[5]

Class:IdReaction:2161885
_displayName72) Arachidonic acid is epoxidated to 14,15-EET by CYP[5]
_timestamp2016-07-15 23:49:39
catalystActivity[CatalystActivity:2161882] monooxygenase activity of CYP(5) [endoplasmic reticulum membrane]
compartment[Compartment:12045] endoplasmic reticulum membrane
created[InstanceEdit:2161780] Williams, MG, 2012-03-14
input[SimpleEntity:29768] AA [cytosol]
[SimpleEntity:29368] O2 [cytosol]
[SimpleEntity:29364] NADPH [cytosol]
[SimpleEntity:70106] H+ [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:2162004] Metabolism of retinoids and arachidonic acid by human and mouse cytochrome P450 1b1
[LiteratureReference:2161833] Analysis of cytochrome P450 metabolites of arachidonic and linoleic acids by liquid chromatography-mass spectrometry with ion trap MS
[LiteratureReference:2161944] Arachidonic acid metabolism by human cytochrome P450s 2C8, 2C9, 2E1, and 1A2: regioselective oxygenation and evidence for a role for CYP2C enzymes in arachidonic acid epoxygenation in human liver microsomes
[LiteratureReference:215077] Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart
modified[InstanceEdit:8879177] Wu, G, 2016-07-15
name72) Arachidonic acid is epoxidated to 14,15-EET by CYP[5]
output[SimpleEntity:2142792] 14,15-EET [cytosol]
[SimpleEntity:29366] NADP+ [cytosol]
[SimpleEntity:29356] H2O [cytosol]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8900393] R-HSA-2161885.1
summation[Summation:2161827] Several cytochrome P450s (CYPs) convert arachidonic acid to ...
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No pathways have been reviewed or authored by 72) Arachidonic acid is epoxidated to 14,15-EET by CYP[5] (2161885)
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