Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+

Class:Id	Reaction:2160884
_displayName	HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+
_doRelease	TRUE
_timestamp	2014-02-20 15:16:12
authored	[InstanceEdit:2160887] Jassal, B, 2012-03-05
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:2160887] Jassal, B, 2012-03-05
edited	[InstanceEdit:2160887] Jassal, B, 2012-03-05
input	[Complex:2160889] HA:HAR:HYAL2 [plasma membrane] [Homo sapiens] [Complex:5333682] SLC9A1:p-CHP:Ca2+ [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:2160910] CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion [LiteratureReference:5333755] A calcineurin homologous protein inhibits GTPase-stimulated Na-H exchange [LiteratureReference:5333769] Role of calcineurin B homologous protein in pH regulation by the Na+/H+ exchanger 1: tightly bound Ca2+ ions as important structural elements [LiteratureReference:5333746] Solution structure of the cytoplasmic region of Na+/H+ exchanger 1 complexed with essential cofactor calcineurin B homologous protein 1 [LiteratureReference:5333709] Calcineurin homologous protein as an essential cofactor for Na+/H+ exchangers
modified	[InstanceEdit:2161486] Jassal, B, 2012-03-14 [InstanceEdit:2161487] Jassal, B, 2012-03-14 [InstanceEdit:2162219] Jassal, B, 2012-03-16 [InstanceEdit:2247519] Jassal, B, 2012-05-14 [InstanceEdit:2428935] Jassal, B, 2012-08-09 [InstanceEdit:5333641] Jassal, Bijay, 2014-02-20 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ HYAL2 interacts with NHE1 to create an acidic environment
output	[Complex:2160891] HA:HAR:HYAL2:SLC9A1:pCHP:Ca2+ [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:2160915] Receptor-mediated uptake of HA [Homo sapiens] [Polymerisation:2160851] HAS1,2,3 mediate the polymerization and export of HA [Homo sapiens] [Reaction:5693356] CEMIP hydrolyzes HA [Homo sapiens] [BlackBoxEvent:9941244] ROS/RNS degrade HA [Homo sapiens] [BlackBoxEvent:9941055] SPAM1 randomly cleaves HA [Homo sapiens]
releaseDate	2012-06-12
reviewed	[InstanceEdit:2172129] D'Eustachio, P, 2012-03-28
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2294779] R-HSA-2160884.2
summation	[Summation:2160856] Hyaluronidases are only active in acidic environments. HYAL2...
(hasEvent)	[Pathway:2160916] Hyaluronan degradation [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9786802] Update Tracker - [Reaction:2160884] HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ - v48:[addLiteratureReference, add_removeInput, modifyText]
[Change default viewing format]

No pathways have been reviewed or authored by HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ (2160884)