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Details on Person Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix

Class:Id	Reaction:216050
_displayName	Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix
_doRelease	TRUE
_timestamp	2013-08-15 15:11:04
authored	[InstanceEdit:266384] Geiger, B, Horwitz, R, 2008-05-07 08:30:32
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:216049] Garapati, P V, 2008-03-11 10:16:02
edited	[InstanceEdit:216084] Garapati, P V, 2008-03-11 10:20:45
input	[DefinedSet:4205071] Integrin alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 [plasma membrane] [Homo sapiens] [Polymer:2327729] Fibronectin matrix [extracellular region] [Homo sapiens]
literatureReference	[LiteratureReference:215376] VLA-4-fibronectin interaction is required for the terminal differentiation of human bone marrow cells capable of spontaneous and high rate immunoglobulin secretion [LiteratureReference:215314] Effect of the interaction between fibronectin and VLA-4 on the proliferation of human B cells, especially a novel human B-cell line, OPM-3
modified	[InstanceEdit:216304] Garapati, P V, 2008-03-11 17:03:18 [InstanceEdit:265247] Garapati, P V, 2008-04-16 08:58:21 [InstanceEdit:266119] Garapati, P V, 2008-04-22 13:10:44 [InstanceEdit:266361] Gopinathrao, G, 2008-05-06 15:10:28 [InstanceEdit:266362] Gopinathrao, G, 2008-05-06 18:16:31 [InstanceEdit:266397] Garapati, P V, 2008-05-07 10:23:53 [InstanceEdit:353628] Garapati, P V, 2008-06-13 10:14:34 [InstanceEdit:920202] Garapati, P V, 2010-08-04 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:4205070] Jupe, S, 2013-08-15 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix
output	[Complex:216035] Integrin alpha4beta1, alpha8beta1, alphaVbeta6:Fibronectin matrix [plasma membrane] [Homo sapiens]
releaseDate	2008-06-30
reviewed	[InstanceEdit:266386] Yamada, K, Humphries, MJ, Hynes, R, 2008-05-07 08:53:37
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:362038] R-HSA-216050.2
summation	[Summation:4205074] Several integrins are able to bind fibronectin (FN1). Alpha5...
(hasEvent)	[Pathway:216083] Integrin cell surface interactions [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9787249] Update Tracker - [Reaction:216050] Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix - v46:[add_removeInput, add_removeSummation]
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