Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person SPP1 [extracellular region]

Class:IdEntityWithAccessionedSequence:215967
_displayNameSPP1 [extracellular region]
_timestamp2013-08-07 15:51:41
compartment[Compartment:984] extracellular region
created[InstanceEdit:215966] Garapati, P V, 2008-03-10 17:58:59
endCoordinate314
modified[InstanceEdit:2796108] Jupe, S, 2012-12-11
[InstanceEdit:2867920] Jupe, S, 2012-12-19
[InstanceEdit:3632907] Wu, G, 2013-05-28
[InstanceEdit:4085154] Orlic-Milacic, M, 2013-08-02
[InstanceEdit:4086236] Jupe, S, 2013-08-07
nameSPP1
Bone sialoprotein 1
Osteopontin
Secreted phosphoprotein 1
referenceEntity[ReferenceGeneProduct:61022] UniProt:P10451 SPP1 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:362360] R-HSA-215967.1
startCoordinate17
(hasComponent)[Complex:216006] Integrin alpha8beta1:SPP1 [plasma membrane] [Homo sapiens]
[Complex:265417] SPP1:Integrin alpha5beta1, alpha9beta1 [plasma membrane] [Homo sapiens]
[Complex:2752110] SPP1:CD44 [plasma membrane] [Homo sapiens]
[Complex:2752112] SPP1:Integrin alpha4beta1 [plasma membrane] [Homo sapiens]
[Complex:2752132] SPP1:Integrin alphaVBeta1,3,5 [plasma membrane] [Homo sapiens]
[Complex:2752139] Osteopontin:Integrins alphaVbeta1,3,5 [plasma membrane] [Rattus norvegicus]
[Complex:4085134] Osteopontin:Integrin alpha8beta1 [plasma membrane] [Homo sapiens]
[Complex:9924011] Integrin alphaVbeta3:SPP1 [plasma membrane] [Homo sapiens]
(hasMember)[DefinedSet:381946] Extracellular matrix ligands [extracellular region] [Homo sapiens]
(input)[Reaction:216061] SPP1 (osteopontin) binds integrin alpha8beta1 [Homo sapiens]
[Reaction:265424] SPP1 (osteopontin) binds integrin alpha5beta1, alpha9beta1 [Homo sapiens]
[Reaction:2752115] SPP1 (osteopontin) binds CD44 [Homo sapiens]
[Reaction:2752118] SPP1 (osteopontin) binds Integrin alpha4beta1 [Homo sapiens]
[Reaction:2752124] Osteopontin binds Integrins alphaVbeta1, 3, 5 [Homo sapiens]
[Reaction:2752125] SPP1 (osteopontin) binds integrins alphaVbeta1, alphaVbeta3, alphaVbeta5 [Homo sapiens]
[Reaction:4085131] Osteopontin binds integrin alpha8beta1 [Mus musculus]
[Reaction:4086205] OPN (osteopontin) degradation by MMP3, MMP7 [Homo sapiens]
(output)[BlackBoxEvent:8952442] SPP1 gene expression is stimulated by RUNX3 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9876393] Update Tracker - [EntityWithAccessionedSequence:215967] SPP1 [extracellular region] - v44:[addName]
[_UpdateTracker:9880618] Update Tracker - [EntityWithAccessionedSequence:215967] SPP1 [extracellular region] - v45:[addName]
[_UpdateTracker:9887734] Update Tracker - [EntityWithAccessionedSequence:215967] SPP1 [extracellular region] - v46:[modifyEndCoordinate, modifyName]
[Change default viewing format]
No pathways have been reviewed or authored by SPP1 [extracellular region] (215967)
Follow Reactome