Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person CACT and DL dimer are phosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex'

Class:Id	Reaction:214845
_displayName	CACT and DL dimer are phosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex'
_doRelease	TRUE
_timestamp	2018-03-09 00:11:47
authored	[InstanceEdit:386948] Williams, MG, 2007-07-11 16:49:12
catalystActivity	[CatalystActivity:208940] protein serine/threonine kinase activity of unknown kinase [cytosol]
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:214841] Williams, MG, 2008-02-26 12:28:44
edited	[InstanceEdit:5490376] Williams, MG, 2014-05-20
figure	[Figure:358131] /figures/DrosTollImdC18.jpg
input	[Complex:214758] SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL:DL dimer:CACT [plasma membrane] [Drosophila melanogaster] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol]
literatureReference	[LiteratureReference:208392] Separable and redundant regulatory determinants in Cactus mediate its dorsal group dependent degradation [LiteratureReference:208075] A gradient of cactus protein degradation establishes dorsoventral polarity in the Drosophila embryo [LiteratureReference:214840] Nuclear import of the Drosophila Rel protein Dorsal is regulated by phosphorylation [LiteratureReference:214865] Cactus-independent regulation of Dorsal nuclear import by the ventral signal
modified	[InstanceEdit:358126] Williams, MG, 2008-06-19 09:29:42 [InstanceEdit:372363] Williams, MG, 2008-06-23 10:13:54 [InstanceEdit:386957] Williams, MG, 2008-11-27 14:37:44 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9024533] Matthews, Lisa, 2017-10-05 [InstanceEdit:9038602] D'Eustachio, Peter, 2018-03-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CACT and DL dimer are phosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex'
output	[Complex:214749] SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL:Phospho DL dimer:Phospho CACT [plasma membrane] [Drosophila melanogaster] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[Reaction:214880] DL dimer binds to TUB and phosphorylated PLL in TL:WEK:MYD88:TUB:PLL 'signalling complex' [Drosophila melanogaster] [Reaction:214859] Activated PLL kinase is autophosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex' [Drosophila melanogaster]
releaseDate	2017-09-12
reviewed	[InstanceEdit:386956] Silverman, N, Lemaitre, B, 2008-06-20 10:21:55
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:56210] Drosophila melanogaster
stableIdentifier	[StableIdentifier:8893254] R-DME-214845.4
summation	[Summation:214263] Pelle (PLL) may be the kinase that phosphorylates both Cactu...
(hasEvent)	[Pathway:214844] DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex' [Drosophila melanogaster]
(precedingEvent)	[Reaction:214847] Phosphorylated CACT and DL dimer dissociate from the TL:WEK:MYD88:TUB:PLL 'signalling complex' [Drosophila melanogaster]
[Change default viewing format]

No pathways have been reviewed or authored by CACT and DL dimer are phosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex' (214845)