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Details on Person Monomeric PGN binds to PGRP-LE in the cytosol

Class:Id	Reaction:214410
_displayName	Monomeric PGN binds to PGRP-LE in the cytosol
_doRelease	TRUE
_timestamp	2018-03-09 00:15:05
authored	[InstanceEdit:386948] Williams, MG, 2007-07-11 16:49:12
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:214403] Williams, MG, 2008-02-26 12:03:36
edited	[InstanceEdit:5490376] Williams, MG, 2014-05-20
figure	[Figure:358151] /figures/DrosTollImdC27.jpg
input	[SimpleEntity:214401] Mono PGN [cytosol] [EntityWithAccessionedSequence:214412] PGRP-LE [cytosol] [Drosophila melanogaster]
literatureReference	[LiteratureReference:208161] Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins [LiteratureReference:208221] PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan
modified	[InstanceEdit:358152] Williams, MG, 2008-06-19 09:33:31 [InstanceEdit:372363] Williams, MG, 2008-06-23 10:13:54 [InstanceEdit:386960] Williams, MG, 2008-11-27 15:03:15 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9024541] Matthews, Lisa, 2017-10-05 [InstanceEdit:9038602] D'Eustachio, Peter, 2018-03-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Monomeric PGN binds to PGRP-LE in the cytosol
output	[Complex:214396] Mono PGN:PGRP-LE [cytosol] [Drosophila melanogaster]
releaseDate	2017-09-12
reviewed	[InstanceEdit:386956] Silverman, N, Lemaitre, B, 2008-06-20 10:21:55
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:56210] Drosophila melanogaster
stableIdentifier	[StableIdentifier:8891792] R-DME-214410.4
summation	[Summation:214261] Peptidoglycan recognition protein, PGRP-LE receptor contains...
(hasEvent)	[Pathway:209171] Peptidoglycans (PGN) bind to a peptidoglycan recognition protein receptor, PGRP-LC/LE [Drosophila melanogaster]
(precedingEvent)	[BlackBoxEvent:214395] Monomeric PGN bound PGRP-LE oligomerises in the cytosol [Drosophila melanogaster]
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