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Details on Person Peptidoglycan recognition protein, PGRP-LE receptor contains...
| Class:Id | Summation:214261 |
|---|---|
| _displayName | Peptidoglycan recognition protein, PGRP-LE receptor contains... |
| _timestamp | 2008-02-26 11:58:08 |
| created | [InstanceEdit:214267] Williams, MG, 2008-02-26 11:58:01 |
| text | Peptidoglycan recognition protein, PGRP-LE receptor contains no predicted transmembrane domain or signal sequence and so is predicted to be an intracellular receptor. The recognition of the monomeric diaminopimelic acid (DAP)-type peptidoglycan (PGN) tracheal cytotoxin, TCT by PGRP-LE occurs intracellularly. However, it is postulated that the PGRP domain of a truncated PGRP-LE can also function outside the cell in a CD14-like manner by presenting DAP-type PGNs to cell surface PGRP-LC receptors. |
| (summation) | [Reaction:214410] Monomeric PGN binds to PGRP-LE in the cytosol [Drosophila melanogaster] |
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No pathways have been reviewed or authored by Peptidoglycan recognition protein, PGRP-LE receptor contains... (214261)
