Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person Pelle (PLL) may be the kinase that phosphorylates both Cactu...
| Class:Id | Summation:214260 |
|---|---|
| _displayName | Pelle (PLL) may be the kinase that phosphorylates both Cactu... |
| _timestamp | 2008-06-19 09:34:14 |
| created | [InstanceEdit:214267] Williams, MG, 2008-02-26 11:58:01 |
| modified | [InstanceEdit:358161] Williams, MG, 2008-06-19 09:34:32 |
| text | Pelle (PLL) may be the kinase that phosphorylates both Cactus (CACT) and the Dorsal/Dorsal-related immunity factor (DL/DIF) homodimer but the biochemical evidence for this is currently inconclusive. DL/DIF homodimer is phosphorylated while associated with CACT. DL is phosphorylated on Ser317 while DIF is very likely to be phosphorylated at Ser348 (inferred from DL). CACT is phosphorylated in its N-terminal half within the first 125 residues. In this region, there are two IKK target-like motifs, involving Ser74 and Ser78 in one, and Ser116 in the other. However, it is not clear which of these residues need to be phosphorylated. |
| (summation) | [Reaction:214860] CACT and DL/DIF dimer are phosphorylated in TL:MYD88:TUB:PLL 'signalling complex' [Drosophila melanogaster] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by Pelle (PLL) may be the kinase that phosphorylates both Cactu... (214260)
