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Details on Person Disassociation of PLC-gamma1 from SLP-76

Class:Id	Reaction:213407
_displayName	Disassociation of PLC-gamma1 from SLP-76
_doRelease	TRUE
_timestamp	2008-06-20 09:43:40
authored	[InstanceEdit:211006] Rudd, C.E., de Bono, B, Garapati, P V, 2008-01-24 15:53:10
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:213409] Garapati, P V, 2008-02-26 10:30:41
input	[Complex:202302] phosphorylated PLC-gamma1 bound to SLP-76 [plasma membrane] [Homo sapiens]
literatureReference	[LiteratureReference:202392] The mechanism of phospholipase C-gamma1 regulation
modified	[InstanceEdit:213416] Garapati, P V, 2008-02-26 11:07:28 [InstanceEdit:213435] Garapati, P V, 2008-02-26 11:25:26 [InstanceEdit:214480] Garapati, P V, 2008-02-26 12:04:24 [InstanceEdit:215251] Gopinathrao, G, 2008-02-27 21:37:06 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Disassociation of PLC-gamma1 from SLP-76
output	[EntityWithAccessionedSequence:202357] p-Y771,Y783,Y1254-PLCG1 [cytosol] [Homo sapiens] [Complex:202162] p-Y113,128,145-SLP-76:GADS:LAT [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:202248] Phosphorylation of PLC-gamma1 [Homo sapiens] [Reaction:202331] Recruitment of PLC-gamma1 to SLP-76 [Homo sapiens] [Reaction:202212] Recruitment of PLC-gamma1 to LAT [Homo sapiens] [Reaction:202375] Recruitment of ITK to SLP-76 [Homo sapiens]
releaseDate	2008-03-12
reviewed	[InstanceEdit:214481] Trowsdale, J, 2008-02-26 12:02:59
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:361210] R-HSA-213407.2
summation	[Summation:213408] The activated PLC-gamma1 detaches from its substrate SLP-76 ...
(hasEvent)	[Pathway:202433] Generation of second messenger molecules [Homo sapiens]
(precedingEvent)	[Reaction:202354] Translocation of PLC-gamma1 to PIP2 [Homo sapiens]
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No pathways have been reviewed or authored by Disassociation of PLC-gamma1 from SLP-76 (213407)