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Details on Person Complement factor H binds to surface-bound C3b

Class:Id	Reaction:2132277
_displayName	Complement factor H binds to surface-bound C3b
_doRelease	TRUE
_timestamp	2017-04-28 20:48:45
authored	[InstanceEdit:2869458] Shamovsky, V, 2012-12-20
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:2132292] Shamovsky, V, 2012-02-21
edited	[InstanceEdit:5149549] Shamovsky, V, 2013-11-19
inferredFrom	[Reaction:981728] Factor H binds to membrane-associated C3b [Homo sapiens]
input	[EntityWithAccessionedSequence:2132241] CFH [extracellular region] [Gallus gallus] [Complex:2132202] C3b [plasma membrane] [Gallus gallus]
isChimeric	FALSE
literatureReference	[LiteratureReference:2314669] Molecular mechanisms of target recognition in an innate immune system: interactions among factor H, C3b, and target in the alternative pathway of human complement
modified	[InstanceEdit:2314544] Shamovsky, V, 2012-06-07 [InstanceEdit:2530595] Shamovsky, V, 2012-10-17 [InstanceEdit:2859048] Shamovsky, V, 2012-12-19 [InstanceEdit:3009248] Shamovsky, V, 2013-02-05 [InstanceEdit:3465608] Shamovsky, V, 2013-05-17 [InstanceEdit:3632869] Shamovsky, V, 2013-05-28 [InstanceEdit:3632870] Shamovsky, V, 2013-05-28 [InstanceEdit:5083130] Shamovsky, V, 2013-11-05 [InstanceEdit:5149551] Matthews, L, 2013-11-20 [InstanceEdit:5324712] Shamovsky, V, 2014-02-18 [InstanceEdit:8986547] Shamovsky, Veronica, 2017-04-28 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Complement factor H binds to surface-bound C3b
output	[Complex:2132251] CFH:C3b [plasma membrane] [Gallus gallus]
precedingEvent	[Reaction:2132085] Cleavage of C3 by surface-bound C3 convertases [Gallus gallus] [Reaction:2132222] Cleavage of factor B to form classical C3 convertase [Gallus gallus] [Reaction:2132100] Fluid-phase proteolytic cleavage of factor B [Gallus gallus] [Reaction:2132074] Cleavage of surface-bound factor B [Gallus gallus]
releaseDate	2014-03-12
reviewed	[InstanceEdit:2562608] D'Eustachio, P, 2012-11-06 [InstanceEdit:3006589] Jupe, S, 2013-01-31
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:49591] Gallus gallus
stableIdentifier	[StableIdentifier:5644387] R-GGA-2132277.3
summation	[Summation:2859040] Mammalian factor H (CFH or FH) can bind both fluid phase and...
(hasEvent)	[Pathway:2132281] Regulation of complement cascades [Gallus gallus]
(precedingEvent)	[Reaction:2132260] Complement factor I inactivates surface-bound C3b [Gallus gallus]
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No pathways have been reviewed or authored by Complement factor H binds to surface-bound C3b (2132277)