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Details on Person CYP3A4,5 oxidise AFB1 to AFXBO

Class:IdReaction:213175
_displayNameCYP3A4,5 oxidise AFB1 to AFXBO
_doReleaseTRUE
_timestamp2014-05-09 15:35:08
authored[InstanceEdit:350358] Jassal, Bijay, 2008-05-19
catalystActivity[CatalystActivity:213161] monooxygenase activity of Cytochrome P450 (CYP3A5 based) [endoplasmic reticulum membrane]
compartment[Compartment:12045] endoplasmic reticulum membrane
[Compartment:17957] endoplasmic reticulum lumen
created[InstanceEdit:213140] Jassal, B, 2008-02-21 14:18:20
edited[InstanceEdit:350358] Jassal, Bijay, 2008-05-19
input[SimpleEntity:156522] AFB1 [endoplasmic reticulum lumen]
[SimpleEntity:113534] O2 [endoplasmic reticulum lumen]
[SimpleEntity:113601] NADPH [endoplasmic reticulum lumen]
[SimpleEntity:156540] H+ [endoplasmic reticulum lumen]
literatureReference[LiteratureReference:213142] Increased levels of aflatoxin-albumin adducts are associated with CYP3A5 polymorphisms in The Gambia, West Africa
[LiteratureReference:5423613] The kinetics of aflatoxin B1 oxidation by human cDNA-expressed and human liver microsomal cytochromes P450 1A2 and 3A4
modified[InstanceEdit:213181] Jassal, B, 2008-02-21 14:19:49
[InstanceEdit:350661] Jassal, Bijay, 2008-05-20
[InstanceEdit:351777] Jassal, B, 2008-05-28 08:44:17
[InstanceEdit:352324] Jassal, B, 2008-06-02 12:56:30
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:2656455] D'Eustachio, P, 2012-11-23
[InstanceEdit:5423614] Jassal, Bijay, 2014-05-09
[InstanceEdit:5423722] Jassal, Bijay, 2014-05-09
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameCYP3A4,5 oxidise AFB1 to AFXBO
output[SimpleEntity:156523] AFXBO [endoplasmic reticulum lumen]
[SimpleEntity:113519] H2O [endoplasmic reticulum lumen]
[SimpleEntity:113564] NADP+ [endoplasmic reticulum lumen]
releaseDate2008-06-30
reviewed[InstanceEdit:351775] D'Eustachio, P, 2008-05-28 08:30:54
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:361303] R-HSA-213175.2
summation[Summation:213138] Aflatoxins are produced by the fungal molds Aspergillus flav...
(hasEvent)[Pathway:211981] Xenobiotics [Homo sapiens]
(updatedInstance)[_UpdateTracker:9786456] Update Tracker - [Reaction:213175] CYP3A4,5 oxidise AFB1 to AFXBO - v49:[addLiteratureReference, modifyText]
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