Query author contributions in Reactome
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Details on Person Immediately after assembly in the ER nonameric (alpha beta:I...
| Class:Id | Summation:2130703 |
|---|---|
| _displayName | Immediately after assembly in the ER nonameric (alpha beta:I... |
| _timestamp | 2012-05-03 15:09:58 |
| created | [InstanceEdit:2130630] Garapati, P V, 2012-02-21 |
| literatureReference | [LiteratureReference:2130329] MHC II and the endocytic pathway: regulation by invariant chain [LiteratureReference:2132037] How MHC class II molecules acquire peptide cargo: biosynthesis and trafficking through the endocytic pathway [LiteratureReference:2213062] The role of endosomes and lysosomes in MHC class II functioning [LiteratureReference:2213082] A structural view of the COPII vesicle coat |
| modified | [InstanceEdit:2213059] Garapati, P V, 2012-04-30 [InstanceEdit:2220950] Jupe, S, 2012-05-03 |
| text | Immediately after assembly in the ER nonameric (alpha beta:Ii)3 complexes egress from ER, facilitated by the presence of Ii, and enter the Golgi complex (Wolf & Ploegh 1995, Geuze 1998). Incorrectly folded or oligomerized alpha, beta and Ii chains are retained in the ER and degraded. The Sec23/24-Sar1 pre-budding complex binds to the nonameric complex and then recruits Sec13/31 outer shell, which buds off from the membrane as a coat protein complex II (COPII) vesicle to be transported to the Golgi complex (Bickford et al. 2004). |
| (summation) | [Reaction:2130731] Formation of COPII vesicle [Homo sapiens] |
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No pathways have been reviewed or authored by Immediately after assembly in the ER nonameric (alpha beta:I... (2130703)
