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Details on Person MHC class II antigen internalization

Class:Id	BlackBoxEvent:2130627
_displayName	MHC class II antigen internalization
_doRelease	TRUE
_timestamp	2012-05-31 09:47:29
authored	[InstanceEdit:2132294] Garapati, P V, 2012-02-21
compartment	[Compartment:984] extracellular region [Compartment:161320] lysosomal lumen
created	[InstanceEdit:2130630] Garapati, P V, 2012-02-21
edited	[InstanceEdit:2132294] Garapati, P V, 2012-02-21
input	[OtherEntity:983667] Antigen [extracellular region]
isChimeric	FALSE
literatureReference	[LiteratureReference:2130715] Endocytosis and molecular sorting [LiteratureReference:1236642] Mechanisms of endocytosis [LiteratureReference:2130592] Phagosomes are fully competent antigen-processing organelles that mediate the formation of peptide:class II MHC complexes [LiteratureReference:2130661] Processing of Mycobacterium tuberculosis antigen 85B involves intraphagosomal formation of peptide-major histocompatibility complex II complexes and is inhibited by live bacilli that decrease phagosome maturation
modified	[InstanceEdit:2213242] Garapati, P V, 2012-04-30 [InstanceEdit:2214370] Garapati, P V, 2012-05-01 [InstanceEdit:2247929] Garapati, P V, 2012-05-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	MHC class II antigen internalization
output	[OtherEntity:2213221] Antigen [lysosomal lumen]
releaseDate	2012-06-12
reviewed	[InstanceEdit:2247930] Neefjes, Jacques, 2012-05-14
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2295045] R-HSA-2130627.2
summation	[Summation:2213095] MHC II typically presents antigens derived from exogenous pr...
(hasEvent)	[Pathway:2132295] MHC class II antigen presentation [Homo sapiens] [Pathway:2132296] Class II antigen processing [Homo sapiens]
(precedingEvent)	[Reaction:2213240] Reduction of disulphide bonds in MHC II antigens [Homo sapiens]
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No pathways have been reviewed or authored by MHC class II antigen internalization (2130627)