Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person STRAP binds both TGF-beta receptor and SMAD7, and stabilizes...
| Class:Id | Summation:2130223 |
|---|---|
| _displayName | STRAP binds both TGF-beta receptor and SMAD7, and stabilizes... |
| _timestamp | 2012-04-13 18:26:14 |
| created | [InstanceEdit:2130224] Orlic-Milacic, M, 2012-02-21 |
| literatureReference | [LiteratureReference:2128996] STRAP and Smad7 synergize in the inhibition of transforming growth factor beta signaling |
| modified | [InstanceEdit:2197664] Orlic-Milacic, M, 2012-04-13 |
| text | STRAP binds both TGF-beta receptor and SMAD7, and stabilizes interaction of phosphorylated TGF-beta receptor complex with SMAD7.This reaction may involve oligomerization of STRAP. STRAP and SMAD7 act synergistically to inhibit the transcription of TGF-beta target genes by preventing SMAD2 and SMAD3 from binding phosphorylated TGFBR1. |
| (summation) | [Reaction:2128994] STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 [Homo sapiens] [Reaction:9846258] GOCAM STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by STRAP binds both TGF-beta receptor and SMAD7, and stabilizes... (2130223)
