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Details on Person STRAP (serine-threonine kinase receptor-associated protein) ...
| Class:Id | Summation:2127610 |
|---|---|
| _displayName | STRAP (serine-threonine kinase receptor-associated protein) ... |
| _timestamp | 2013-08-15 19:46:43 |
| created | [InstanceEdit:2127611] Orlic-Milacic, M, 2012-02-16 |
| literatureReference | [LiteratureReference:2127560] Identification of STRAP, a novel WD domain protein in transforming growth factor-beta signaling |
| modified | [InstanceEdit:2197664] Orlic-Milacic, M, 2012-04-13 [InstanceEdit:2197821] Orlic-Milacic, M, 2012-04-16 [InstanceEdit:4218343] Orlic-Milacic, M, 2013-08-15 |
| text | STRAP (serine-threonine kinase receptor-associated protein) binds to the activated TGF-beta receptor complex. In in vitro studies, STRAP is able to bind both TGFBR1 and TGFBR2 (Datta et al. 1998). This was deduced from experiments in which a recombinant mouse Strap and recombinant human TGFBR1 and TGFBR2 were expressed in COS1 cells. STRAP is also able to bind unphosphorylated TGF-beta receptor complex, but the physiological significance, if any, of this interaction is not known. |
| (summation) | [Reaction:2127562] STRAP binds phosphorylated TGF-beta receptor complex [Homo sapiens] [Reaction:9846240] GOCAM STRAP binds phosphorylated TGF-beta receptor complex [Homo sapiens] |
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No pathways have been reviewed or authored by STRAP (serine-threonine kinase receptor-associated protein) ... (2127610)
