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Details on Person NOTCH2 stimulates transcription of FCER2 (CD23A)

Class:Id	BlackBoxEvent:2127285
_displayName	NOTCH2 stimulates transcription of FCER2 (CD23A)
_doRelease	TRUE
_timestamp	2013-05-31 09:40:21
authored	[InstanceEdit:2980678] Orlic-Milacic, M, 2013-01-11
compartment	[Compartment:7660] nucleoplasm [Compartment:876] plasma membrane
created	[InstanceEdit:2127286] Orlic-Milacic, M, 2012-02-14
edited	[InstanceEdit:3159303] Haw, R, 2013-01-14
input	[EntityWithAccessionedSequence:2127282] FCER2 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:2127284] Notch2 is involved in the overexpression of CD23 in B-cell chronic lymphocytic leukemia
modified	[InstanceEdit:2127291] Orlic-Milacic, M, 2012-02-14 [InstanceEdit:2127543] Orlic-Milacic, M, 2012-02-15 [InstanceEdit:2197565] Orlic-Milacic, M, 2012-04-12 [InstanceEdit:2976744] Orlic-Milacic, M, 2013-01-10 [InstanceEdit:2980008] Orlic-Milacic, M, 2013-01-10 [InstanceEdit:2980678] Orlic-Milacic, M, 2013-01-11 [InstanceEdit:3301377] Orlic-Milacic, M, 2013-04-22 [InstanceEdit:3446783] Orlic-Milacic, M, 2013-05-15 [InstanceEdit:3446784] Orlic-Milacic, M, 2013-05-15 [InstanceEdit:3448658] Orlic-Milacic, M, 2013-05-15 [InstanceEdit:3451015] Orlic-Milacic, M, 2013-05-16 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	NOTCH2 stimulates transcription of FCER2 (CD23A)
output	[EntityWithAccessionedSequence:2127280] FCER2(1-321) [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:2976742] NOTCH2 coactivator complex binds FCER2 promoter [Homo sapiens] [Reaction:2197588] NICD2 binds RBPJ and MAML in the nucleus [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:2127288] Positive gene expression regulation by 'NOTCH2 Coactivator Complex:FCER2 gene [nucleoplasm]'
regulationReference	[RegulationReference:9642020] Positive gene expression regulation by 'NOTCH2 Coactivator Complex:FCER2 gene [nucleoplasm]' Notch2 is involved in the overexpression of CD23 in B-cell chronic lymphocytic leukemia
releaseDate	2013-06-11
reviewed	[InstanceEdit:3448657] Boyle, Scott, 2013-04-25 [InstanceEdit:3448655] Ilagan, Ma Xenia, 2013-04-25
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:3654290] R-HSA-2127285.4
summation	[Summation:2127540] Transient transfection of a human pre-B-cell line REH with a...
(hasEvent)	[Pathway:2197563] NOTCH2 intracellular domain regulates transcription [Homo sapiens]
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No pathways have been reviewed or authored by NOTCH2 stimulates transcription of FCER2 (CD23A) (2127285)