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Details on Person Caspase 3-mediated cleavage of PKC delta

Class:Id	Reaction:212552
_displayName	Caspase 3-mediated cleavage of PKC delta
_doRelease	TRUE
_timestamp	2017-11-17 22:16:05
authored	[InstanceEdit:201620] Schulze-Osthoff, K, 2007-09-03 07:52:18
catalystActivity	[CatalystActivity:114327] cysteine-type endopeptidase activity of Caspase-3 [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:212535] Matthews, L, 2008-02-12 15:52:37
edited	[InstanceEdit:201589] Matthews, L, 2007-09-03 07:38:20
input	[EntityWithAccessionedSequence:58200] PRKCD [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:212541] Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis
modified	[InstanceEdit:213059] Matthews, L, 2008-02-19 03:30:32 [InstanceEdit:213301] Matthews, L, 2008-02-25 10:25:58 [InstanceEdit:3009459] Jassal, B, 2013-02-05 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9029450] Orlic-Milacic, Marija, 2017-11-17 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Caspase 3-mediated cleavage of PKC delta
output	[EntityWithAccessionedSequence:212551] PRKCD(330-676) [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:212547] PRKCD(1-329) [cytosol] [Homo sapiens]
precedingEvent	[Reaction:114252] Cleavage of Procaspase-3 by the apoptosome [Homo sapiens] [Reaction:114259] Cleavage of Procaspase‑9 to caspase‑9 [Homo sapiens] [Reaction:114419] Dissociation of Caspase-3 from DIABLO:XIAP:Caspase-3 [Homo sapiens] [Reaction:114306] SMAC binds XIAP:Caspase-3 [Homo sapiens] [Reaction:418845] Activation of caspase-3 [Homo sapiens] [Reaction:373700] Caspase-9 binds DCC:DIP13alpha complex [Homo sapiens]
releaseDate	2005-09-26
reviewed	[InstanceEdit:204051] Ranganathan, S, 2007-11-23 00:10:26
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:359008] R-HSA-212552.4
summation	[Summation:212543] Caspase mediated cleavage produces a constitutively active k...
(hasEvent)	[Pathway:111465] Apoptotic cleavage of cellular proteins [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9787671] Update Tracker - [Reaction:212552] Caspase 3-mediated cleavage of PKC delta - v44:[add_removeInput]
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