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Details on Person Heterochromatin Replication Complex [nucleoplasm]

Class:IdComplex:212082
_displayNameHeterochromatin Replication Complex [nucleoplasm]
_timestamp2023-12-10 09:03:41
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:212086] May, B, Gopinathrao, G, 2008-02-08 19:50:06
hasComponent
literatureReference[LiteratureReference:212100] Np95 is implicated in pericentromeric heterochromatin replication and in major satellite silencing
[LiteratureReference:212120] The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA
[LiteratureReference:212167] UHRF1 plays a role in maintaining DNA methylation in mammalian cells
[LiteratureReference:212110] DNA methyltransferase Dnmt1 associates with histone deacetylase activity
[LiteratureReference:212148] Proliferating cell nuclear antigen associates with histone deacetylase activity, integrating DNA replication and chromatin modification
[LiteratureReference:212163] DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci
[LiteratureReference:212144] Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication
[LiteratureReference:417172] Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway
[LiteratureReference:212024] Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1
[LiteratureReference:417186] In vivo study of the nucleosome assembly functions of ASF1 histone chaperones in human cells
[LiteratureReference:212060] PCNA connects DNA replication to epigenetic inheritance in yeast
[LiteratureReference:417149] The Williams syndrome transcription factor interacts with PCNA to target chromatin remodelling by ISWI to replication foci
modified[InstanceEdit:217333] Gopinathrao, G, 2008-03-26 17:17:58
[InstanceEdit:417154] May, B, 2009-04-11 07:45:44
[InstanceEdit:417212] May, B, 2009-04-12 08:46:12
[InstanceEdit:427731] May, B, 2009-06-25
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:9856083] May, Bruce, 2023-12-10
nameHeterochromatin Replication Complex
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8905780] R-HSA-212082.1
summation[Summation:417211] The full composition and order of assembly of the Heterochro...
(output)[BlackBoxEvent:417138] Formation of Heterochromatin Replication Complex [Homo sapiens]
(physicalEntity)[CatalystActivity:212149] histone deacetylase activity of Heterochromatin Replication Complex [nucleoplasm]
[CatalystActivity:212175] DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates of Heterochromatin Replication Complex [nucleoplasm]
[CatalystActivity:212179] histone H3K9 methyltransferase activity of Heterochromatin Replication Complex [nucleoplasm]
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No pathways have been reviewed or authored by Heterochromatin Replication Complex [nucleoplasm] (212082)
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