Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
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Details on Person Humans, unlike some other organisms, have newly synthesized ...
| Class:Id | Summation:212064 |
|---|---|
| _displayName | Humans, unlike some other organisms, have newly synthesized ... |
| _timestamp | 2010-11-08 11:06:11 |
| created | [InstanceEdit:212086] May, B, Gopinathrao, G, 2008-02-08 19:50:06 |
| modified | [InstanceEdit:416955] May, B, 2009-04-05 10:52:26 [InstanceEdit:417223] May, B, 2009-04-12 08:57:22 [InstanceEdit:427732] May, B, 2009-06-25 [InstanceEdit:996693] May, B, 2010-11-08 |
| text | Humans, unlike some other organisms, have newly synthesized Histone H3 molecules that lack acetyl groups and therefore require no deacetylation before other modifications are made (Sobel et al. 1995). SETDB1, which is bound to methylcytosine via MBD1, methylates histone H3 at lysine-9 (H3K9) (Loyola et al. 2009). Though SETDB1 can trimethylate H3K9 in vitro, it is believed that SETDB1 monomethylates H3K9 in vivo. |
| (summation) | [Reaction:212067] Monomethylation of Histone H3 at Lysine-9 by Heterochromatin Replication Complex [Homo sapiens] |
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No pathways have been reviewed or authored by Humans, unlike some other organisms, have newly synthesized ... (212064)
