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Details on Person CYP3A7 can 6beta-hydroxylate testosterone

Class:Id	Reaction:211882
_displayName	CYP3A7 can 6beta-hydroxylate testosterone
_doRelease	TRUE
_timestamp	2012-11-23 14:37:00
authored	[InstanceEdit:350358] Jassal, Bijay, 2008-05-19
catalystActivity	[CatalystActivity:213160] monooxygenase activity of Cytochrome P450 (CYP3A7 based) [endoplasmic reticulum membrane]
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:211969] Jassal, B, 2008-02-08 15:33:52
edited	[InstanceEdit:350358] Jassal, Bijay, 2008-05-19
input	[SimpleEntity:30321] TES [endoplasmic reticulum lumen] [SimpleEntity:113601] NADPH [endoplasmic reticulum lumen] [SimpleEntity:156540] H+ [endoplasmic reticulum lumen] [SimpleEntity:113534] O2 [endoplasmic reticulum lumen]
literatureReference	[LiteratureReference:213139] Steroid hydroxylation by human fetal CYP3A7 and human NADPH-cytochrome P450 reductase coexpressed in insect cells using baculovirus
modified	[InstanceEdit:213140] Jassal, B, 2008-02-21 14:18:20 [InstanceEdit:350661] Jassal, Bijay, 2008-05-20 [InstanceEdit:351777] Jassal, B, 2008-05-28 08:44:17 [InstanceEdit:352324] Jassal, B, 2008-06-02 12:56:30 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:2656455] D'Eustachio, P, 2012-11-23 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CYP3A7 can 6beta-hydroxylate testosterone
output	[SimpleEntity:213144] 6BHT [endoplasmic reticulum lumen] [SimpleEntity:113519] H2O [endoplasmic reticulum lumen] [SimpleEntity:113564] NADP+ [endoplasmic reticulum lumen]
releaseDate	2008-06-30
reviewed	[InstanceEdit:351775] D'Eustachio, P, 2008-05-28 08:30:54
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360735] R-HSA-211882.2
summation	[Summation:213165] CYP3A7 is only expressed in fetal liver and not in adults. I...
(hasEvent)	[Pathway:211981] Xenobiotics [Homo sapiens]
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No pathways have been reviewed or authored by CYP3A7 can 6beta-hydroxylate testosterone (211882)