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Details on Person Caspase-activated PAK-2 is regulated by subcellular targeting and proteasomal degradation

Class:IdLiteratureReference:211655
_displayNameCaspase-activated PAK-2 is regulated by subcellular targeting and proteasomal degradation
_timestamp2008-02-08 00:35:04
author[Person:211629] Jakobi, R
[Person:211646] McCarthy, CC
[Person:211645] Koeppel, MA
[Person:211649] Stringer, DK
created[InstanceEdit:211652] Matthews, L, 2008-02-08 00:34:04
journalJ Biol Chem
pages38675-85
pubMedIdentifier12853446
titleCaspase-activated PAK-2 is regulated by subcellular targeting and proteasomal degradation
volume278
year2003
(literatureReference)[Summation:211647] p21-activated protein kinase (PAK-2), also known as gamma-P...
[Summation:211684] Following caspase mediated cleavage, PAK-2p34 translocates t...
[Summation:211711] The subcellular localization of PAK-2 is controlled by nucle...
[Summation:211769] Proteolytically activated PAK-2p34, but not full-length PAK-...
[Summation:211770] Stimulation of cell death by PAK-2 requires the generation ...
[Summation:211775] PAK-2p34 is ubiquitinated prior to degradation (Jakobi et al...
[BlackBoxEvent:211715] Proteasome mediated degradation of PAK-2p34 [Homo sapiens]
[Reaction:211725] Interaction of PAK-2p34 with PS-GAP results in accumulation of PAK-2p34 in the perinuclear region [Mus musculus]
[Pathway:211733] Regulation of activated PAK-2p34 by proteasome mediated degradation [Homo sapiens]
[Pathway:211736] Stimulation of the cell death response by PAK-2p34 [Homo sapiens]
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