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Details on Person PAK-2 is fully autophosphorylated at 8 sites upon translocat...

Class:IdSummation:211602
_displayNamePAK-2 is fully autophosphorylated at 8 sites upon translocat...
_timestamp2008-06-13 10:26:49
created[InstanceEdit:211597] Matthews, L, 2008-02-08 00:29:01
literatureReference[LiteratureReference:211590] Regulation of the interaction of Pak2 with Cdc42 via autophosphorylation of serine 141
modified[InstanceEdit:213320] Matthews, L, 2008-02-25 10:34:56
[InstanceEdit:353636] Matthews, L, 2008-06-13 10:24:45
textPAK-2 is fully autophosphorylated at 8 sites upon translocation to the endoplasmic reticulum. Autophosphorylation of Thr-402 in the activation loop opens the catalytic cleft to allow binding of substrates (Jung and Traugh, 2005).
(summation)[Reaction:211594] Activation of Pak2 by autophosphorylation at Thr-402 [Homo sapiens]
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