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Details on Person Autophosphorylation of the insulin receptor triggers a serie...

Class:IdSummation:211566
_displayNameAutophosphorylation of the insulin receptor triggers a serie...
_timestamp2008-02-07 14:01:30
created[InstanceEdit:211573] Schmidt, EE, 2008-02-07 14:01:08
textAutophosphorylation of the insulin receptor triggers a series of signalling events, mediated by SHC or IRS, and resulting in activation of the Ras/RAF and MAP kinase cascades. A second effect of the autophosphorylation of the insulin receptor is its internalisation into an endosome, which downregulates its signalling activity.
(summation)[Pathway:74751] Insulin receptor signalling cascade [Homo sapiens]
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