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Details on Person PDX1-dependent synthesis of NKX6-1 protein

Class:Id	BlackBoxEvent:211350
_displayName	PDX1-dependent synthesis of NKX6-1 protein
_doRelease	TRUE
_timestamp	2018-04-18 14:34:18
authored	[InstanceEdit:351500] Ferrer, J, Tello-Ruiz, MK, 2008-05-23
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:211351] D'Eustachio, P, 2008-02-01 22:29:46
edited	[InstanceEdit:349681] D'Eustachio, P, 2008-05-12 21:43:33
inferredFrom	[BlackBoxEvent:186524] PDX1 transactivates Nkx6.1 [Mus musculus]
input	[EntityWithAccessionedSequence:9606121] NKX6-1 gene [nucleoplasm] [Homo sapiens]
modified	[InstanceEdit:211359] D'Eustachio, P, 2008-02-01 22:30:15 [InstanceEdit:266359] Gopinathrao, G, 2008-05-06 14:37:06 [InstanceEdit:349684] D'Eustachio, P, 2008-05-12 21:51:33 [InstanceEdit:351498] D'Eustachio, P, 2008-05-23 22:55:12 [InstanceEdit:2671770] D'Eustachio, P, 2012-11-25 [InstanceEdit:9606133] Orlic-Milacic, Marija, 2018-04-18 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PDX1-dependent synthesis of NKX6-1 protein
output	[EntityWithAccessionedSequence:210765] NKX6-1 [nucleoplasm] [Homo sapiens]
precedingEvent	[BlackBoxEvent:211272] FOXOA2-, MAFA-, and PAX6-dependent synthesis of PDX1 protein [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:211357] Positive gene expression regulation by 'PDX1 [nucleoplasm]'
releaseDate	2008-06-30
reviewed	[InstanceEdit:349683] Jensen, J, 2008-05-12 21:46:53
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:361927] R-HSA-211350.3
summation	[Summation:211345] In mature beta-cells of the pancreas, the NKX6-1 gene is tra...
(hasEvent)	[Pathway:210745] Regulation of gene expression in beta cells [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9779540] Update Tracker - [BlackBoxEvent:211350] PDX1-dependent synthesis of NKX6-1 protein - v65:[addInput]
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No pathways have been reviewed or authored by PDX1-dependent synthesis of NKX6-1 protein (211350)