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Details on Person Alpha v beta 3 integrin is one of the potential heterophilic...
| Class:Id | Summation:211114 |
|---|---|
| _displayName | Alpha v beta 3 integrin is one of the potential heterophilic... |
| _timestamp | 2008-02-05 13:52:29 |
| created | [InstanceEdit:211109] Garapati, P V, 2008-01-28 10:30:53 |
| literatureReference | [LiteratureReference:211092] Identification of alpha v beta 3 as a heterotypic ligand for CD31/PECAM-1 [LiteratureReference:211069] CD31/PECAM-1 is a ligand for alpha v beta 3 integrin involved in adhesion of leukocytes to endothelium |
| modified | [InstanceEdit:211548] Garapati, P V, 2008-02-05 13:52:09 |
| text | Alpha v beta 3 integrin is one of the potential heterophilic ligands of PECAM-1 that is involved in down-regulation of T-cell responses. The heterophilic interaction of alpha v beta 3 integrin on endothelial cells with PEACAM-1 on leukocytes increases the adhesive function of beta integrins on T cells, monocytes, neutrophils and NK cells suggesting that leukocyte PEACAM-1 act as a signaling molecule. |
| (summation) | [Reaction:210304] Interaction of integrin alphaVbeta3 with PECAM1 [Homo sapiens] |
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No pathways have been reviewed or authored by Alpha v beta 3 integrin is one of the potential heterophilic... (211114)
