Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
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Details on Person Tie2/Tek provide mitogenic signals to endothelial cells by p...
| Class:Id | Summation:210975 |
|---|---|
| _displayName | Tie2/Tek provide mitogenic signals to endothelial cells by p... |
| _timestamp | 2008-02-05 13:52:50 |
| created | [InstanceEdit:210971] Garapati, P V, 2008-01-18 15:29:04 |
| literatureReference | [LiteratureReference:210857] Functional significance of Tie2 signaling in the adult vasculature |
| modified | [InstanceEdit:211548] Garapati, P V, 2008-02-05 13:52:09 |
| text | Tie2/Tek provide mitogenic signals to endothelial cells by promoting the association of Grb2 to one of their phosphotyrosines. Grb2 is an adaptor protein that has been linked to activation of Ras and mitogen activated protein kinase (MAPK) cell growth signaling pathways. Grb2 also binds to the Y1102 of the kinase domain of Tie2 with one of its SH2 doamins. |
| (summation) | [Reaction:204871] Interaction of Tie2 and Grb2 [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by Tie2/Tek provide mitogenic signals to endothelial cells by p... (210975)
