Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person The properties of transcriptional networks in late stage (br...
| Class:Id | Summation:210892 |
|---|---|
| _displayName | The properties of transcriptional networks in late stage (br... |
| _timestamp | 2008-01-17 18:07:43 |
| created | [InstanceEdit:210893] D'Eustachio, P, 2008-01-17 18:07:43 |
| modified | [InstanceEdit:210897] D'Eustachio, P, 2008-01-17 18:07:59 |
| text | The properties of transcriptional networks in late stage (branching morphogenesis) pancreatic bud precursor cells are inferred from the properties of well-studied networks in mouse models. In mice, committed but undifferentiated epithelial cells are organized into branching ductal structures. At a molecular level, expression of Pdx1, Nkx2.2, and Nkx6.1 is reduced while Hnf6 expression remains high. Hnf6 mediates the continued expression of Onecut3 and Hnf1 beta and epithelial cell proliferation. As expression of Ngn3 (corresponds to human NEUROG3) rises, endocrine differentiation of the epithelial cells begins (Servitja and Ferrer 2004; Chakrabarti and Mirmira 2003). |
| (summation) | [Pathway:210744] Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by The properties of transcriptional networks in late stage (br... (210892)
