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Details on Person The p85 subunit of phosphatidylinositol 3-kinase (PI3-kinase...
| Class:Id | Summation:210874 |
|---|---|
| _displayName | The p85 subunit of phosphatidylinositol 3-kinase (PI3-kinase... |
| _timestamp | 2008-02-05 13:52:46 |
| created | [InstanceEdit:210879] Garapati, P V, 2008-01-17 14:13:36 |
| literatureReference | [LiteratureReference:204768] Tyrosine 1101 of Tie2 is the major site of association of p85 and is required for activation of phosphatidylinositol 3-kinase and Akt |
| modified | [InstanceEdit:211548] Garapati, P V, 2008-02-05 13:52:09 |
| text | The p85 subunit of phosphatidylinositol 3-kinase (PI3-kinase) associates with Tie2, most likely at phosphotyrosine 1102. This association leads on to the activation of Akt/PKB, a process linked to cell survival and antiapoptosis, and that may in part account for Tie2's role in vascular growth and maintenance. |
| (summation) | [Reaction:204798] Interaction of Tie2 and p85 of PI3K [Homo sapiens] |
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No pathways have been reviewed or authored by The p85 subunit of phosphatidylinositol 3-kinase (PI3-kinase... (210874)
