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Details on Person Trans-phosphorylation of Tie2

Class:IdReaction:210872
_displayNameTrans-phosphorylation of Tie2
_doReleaseTRUE
_timestamp2009-02-13 12:52:43
authored[InstanceEdit:215562] Garapati, P V, de Bono, B, 2008-03-05 10:26:56
catalystActivity[CatalystActivity:210866] protein tyrosine kinase activity of ANGPT1:TEK [plasma membrane]
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:210879] Garapati, P V, 2008-01-17 14:13:36
inferredFrom
input[Complex:210862] 2xANGPT1:TEK [plasma membrane] [Homo sapiens]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
literatureReference[LiteratureReference:210857] Functional significance of Tie2 signaling in the adult vasculature
modified[InstanceEdit:210989] Garapati, P V, 2008-01-22 15:06:28
[InstanceEdit:211109] Garapati, P V, 2008-01-28 10:30:53
[InstanceEdit:211549] de Bono, B, 2008-02-06 09:45:07
[InstanceEdit:213345] Gopinathrao, G, 2008-02-25 21:36:16
[InstanceEdit:214837] Garapati, P V, 2008-02-26 12:23:14
[InstanceEdit:214882] Garapati, P V, 2008-02-26 12:32:59
[InstanceEdit:215251] Gopinathrao, G, 2008-02-27 21:37:06
[InstanceEdit:215563] Garapati, P V, 2008-03-05 10:30:39
[InstanceEdit:215569] Garapati, P V, 2008-03-05 12:10:33
[InstanceEdit:391188] Garapati, P V, 2009-02-13 12:40:46
[InstanceEdit:391194] Garapati, P V, 2009-02-13 12:52:27
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameTrans-phosphorylation of Tie2
output[Complex:210859] Phosphorylated Tie2 in Tie2/Akt dimer [plasma membrane] [Homo sapiens]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
precedingEvent
releaseDate2008-03-12
reviewed[InstanceEdit:214481] Trowsdale, J, 2008-02-26 12:02:59
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:361236] R-HSA-210872.2
summation[Summation:210876] The dimerization of Tie2 leads to autophosphorylation and ac...
(hasEvent)[Pathway:210993] Tie2 Signaling [Homo sapiens]
(precedingEvent)[Reaction:204773] Interaction of Tie2 and Grb7 [Homo sapiens]
[Reaction:204798] Interaction of Tie2 and p85 of PI3K [Homo sapiens]
[Reaction:204813] Interaction of Tie2 and Grb14 [Homo sapiens]
[Reaction:204850] Interaction of Tie2 and Dok-2 [Homo sapiens]
[Reaction:204861] Interaction of Tie2 and Shc1 [Homo sapiens]
[Reaction:204871] Interaction of Tie2 and Grb2 [Homo sapiens]
[Reaction:204873] Interaction of Tie2 and Shp2 [Homo sapiens]
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