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Details on Person HNF1B- and FGF10-dependent synthesis of PTF1A protein

Class:Id	BlackBoxEvent:210788
_displayName	HNF1B- and FGF10-dependent synthesis of PTF1A protein
_doRelease	TRUE
_timestamp	2018-04-18 13:51:13
authored	[InstanceEdit:351500] Ferrer, J, Tello-Ruiz, MK, 2008-05-23
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:210768] D'Eustachio, P, 2008-01-15 23:30:34
edited	[InstanceEdit:349681] D'Eustachio, P, 2008-05-12 21:43:33
inferredFrom	[BlackBoxEvent:190093] FGF10 activates Ptf1 expression in early pancreatic buds [Mus musculus] [BlackBoxEvent:187247] HNF1b transactivates Ptf1a [Mus musculus]
input	[EntityWithAccessionedSequence:9606080] PTF1A gene [nucleoplasm] [Homo sapiens]
modified	[InstanceEdit:266359] Gopinathrao, G, 2008-05-06 14:37:06 [InstanceEdit:349684] D'Eustachio, P, 2008-05-12 21:51:33 [InstanceEdit:351498] D'Eustachio, P, 2008-05-23 22:55:12 [InstanceEdit:2671770] D'Eustachio, P, 2012-11-25 [InstanceEdit:9606083] Orlic-Milacic, Marija, 2018-04-18 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	HNF1B- and FGF10-dependent synthesis of PTF1A protein
output	[EntityWithAccessionedSequence:210783] PTF1A [nucleoplasm] [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:210759] Positive gene expression regulation by 'FGF10 [extracellular region]' [PositiveGeneExpressionRegulation:210776] Positive gene expression regulation by 'HNF1B [nucleoplasm]'
releaseDate	2008-06-30
reviewed	[InstanceEdit:349683] Jensen, J, 2008-05-12 21:46:53
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:361005] R-HSA-210788.3
summation	[Summation:210786] The PTF1A gene is transcribed, its mRNA is translated, and t...
(hasEvent)	[Pathway:210747] Regulation of gene expression in early pancreatic precursor cells [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9779305] Update Tracker - [BlackBoxEvent:210788] HNF1B- and FGF10-dependent synthesis of PTF1A protein - v65:[addInput] [_UpdateTracker:9787544] Update Tracker - [BlackBoxEvent:210788] HNF1B- and FGF10-dependent synthesis of PTF1A protein - v44:[add_removeRegulator]
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No pathways have been reviewed or authored by HNF1B- and FGF10-dependent synthesis of PTF1A protein (210788)