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Details on Person RNA endonuclease activity of AGO2:duplex siRNA [cytosol]

Class:IdCatalystActivity:2106608
_displayNameRNA endonuclease activity of AGO2:duplex siRNA [cytosol]
_timestamp2024-05-14 19:07:02
activity[GO_MolecularFunction:3196] RNA endonuclease activity
created[InstanceEdit:2106631] May, B, 2012-02-10
modified[InstanceEdit:9658105] Weiser, JD, 2019-08-09
[InstanceEdit:9658105] Weiser, JD, 2019-08-09
[InstanceEdit:9658105] Weiser, JD, 2019-08-09
[InstanceEdit:9658105] Weiser, JD, 2019-08-09
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9666277] Weiser, JD, 2019-11-04
[InstanceEdit:9676538] Cook, Justin, 2020-02-17
[InstanceEdit:9676538] Cook, Justin, 2020-02-17
[InstanceEdit:9676538] Cook, Justin, 2020-02-17
[InstanceEdit:9676538] Cook, Justin, 2020-02-17
[InstanceEdit:9689079] Cook, Justin, 2020-05-15
[InstanceEdit:9689079] Cook, Justin, 2020-05-15
[InstanceEdit:9909910] Weiser, Joel, 2024-05-14
[InstanceEdit:9909910] Weiser, Joel, 2024-05-14
[InstanceEdit:9963749] Weiser, Joel, 2025-08-15
[InstanceEdit:9963749] Weiser, Joel, 2025-08-15
physicalEntity[Complex:2106605] AGO2:duplex siRNA [cytosol] [Homo sapiens]
(catalystActivity)[Reaction:9023912] AGO2 cleaves passenger strand of duplex siRNA [Homo sapiens]
[CatalystActivityReference:9643359] endoribonuclease activity of AGO2:duplex siRNA [cytosol] Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes
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