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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person JAK2 [cytosol]

Class:IdEntityWithAccessionedSequence:210620
_displayNameJAK2 [cytosol]
_timestamp2016-11-29 15:48:14
compartment[Compartment:70101] cytosol
created[InstanceEdit:210618] Williams, MG, 2008-01-15 15:30:58
endCoordinate1132
modified[InstanceEdit:3132750] Wu, G, 2013-02-13
[InstanceEdit:8949827] Jupe, Steve, 2016-11-29
nameJAK2
Tyrosine-protein kinase JAK2
referenceEntity[ReferenceGeneProduct:57647] UniProt:O60674 JAK2 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1107148] R-HSA-210620.2
startCoordinate1
(activeUnit)[CatalystActivity:873920] protein tyrosine kinase activity of IFNG:IFNGR1:JAK1:IFNGR2:JAK2 [plasma membrane]
[CatalystActivity:914083] non-membrane spanning protein tyrosine kinase activity of High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane]
[CatalystActivity:2447206] protein tyrosine kinase activity of JAK2:SFKS:p-KIT complex [plasma membrane]
[CatalystActivity:2586550] protein tyrosine kinase activity of LEP:LEPR:JAK2 [plasma membrane]
[CatalystActivity:9006324] protein tyrosine kinase activity of EPO:EPOR:JAK2:LYN:IRS2 [plasma membrane]
[CatalystActivity:9670409] protein tyrosine kinase activity of KIT mutant dimers:SFKs:JAK2 [plasma membrane]
(hasCandidate)[CandidateSet:5672734] RAF activating kinases [plasma membrane] [Homo sapiens]
[CandidateSet:8987151] JAK2, JAK3 [cytosol] [Homo sapiens]
(hasComponent)[Complex:873808] IFNGR2:JAK2 [plasma membrane] [Homo sapiens]
[Complex:879945] IL3RB:JAK2 [plasma membrane] [Homo sapiens]
[Complex:912316] pY593,Y628-IL3RB:JAK2 [plasma membrane] [Homo sapiens]
[Complex:914033] p(Y593)-Bc:JAK2 [plasma membrane] [Homo sapiens]
[Complex:914173] p-S585-IL3RB:JAK2 [plasma membrane] [Homo sapiens]
[Complex:982774] Growth Hormone Receptor:JAK2 [plasma membrane] [Homo sapiens]
[Complex:1168397] Activated Growth Hormone Receptor:JAK2 [plasma membrane] [Homo sapiens]
[Complex:1169223] Tyrosine phosphorylated Growth Hormone Receptor:JAK2 [plasma membrane] [Homo sapiens]
[Complex:1302663] PRLR:JAK2 [plasma membrane] [Homo sapiens]
[Complex:1370506] p(S349)-PRLR:JAK2 [plasma membrane] [Homo sapiens]
List all 20 refering instances
(hasMember)[CandidateSet:1067656] JAK1, JAK2, (TYK2) [cytosol] [Homo sapiens]
(input)[Reaction:879937] The common beta chain IL3RB binds JAK2 [Homo sapiens]
[Reaction:982792] Growth hormone receptor binds JAK2 [Homo sapiens]
[Reaction:1302698] PRLR associates with JAK2 [Homo sapiens]
[Reaction:1433451] JAK2 binds to p-KIT [Homo sapiens]
[Reaction:6785898] IL4R binds JAK2 [Homo sapiens]
[Reaction:8950063] IL12RB2 binds JAK2 [Homo sapiens]
[Reaction:8950737] IL23R binds JAK2 [Homo sapiens]
[Reaction:9670413] JAK2 binds to p-KIT mutants [Homo sapiens]
[BlackBoxEvent:9676071] CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1 binds and activates JAK2, TYK2, SYK, and HCK [Homo sapiens]
(output)[Reaction:210691] Phosphorylated JAK2 is dephosphorylated by PTP1B [Homo sapiens]
(updatedInstance)[_UpdateTracker:9876052] Update Tracker - [EntityWithAccessionedSequence:210620] JAK2 [cytosol] - v44:[modifyEndCoordinate]
[_UpdateTracker:9895842] Update Tracker - [EntityWithAccessionedSequence:210620] JAK2 [cytosol] - v60:[addName]
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No pathways have been reviewed or authored by JAK2 [cytosol] (210620)