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Details on Person Interaction of DAP12 and KIR3DS1

Class:Id	Reaction:210298
_displayName	Interaction of DAP12 and KIR3DS1
_doRelease	TRUE
_timestamp	2012-09-03 10:23:01
authored	[InstanceEdit:2272794] Garapati, P V, 2012-05-25
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:210296] Garapati, P V, 2008-01-10 13:46:10
edited	[InstanceEdit:2272794] Garapati, P V, 2012-05-25
input	[Complex:548940] DAP12 dimer [plasma membrane] [Homo sapiens] [Complex:2272751] KIR3DS1:HLA-Bw4 [plasma membrane] [Homo sapiens] [Complex:2272751] KIR3DS1:HLA-Bw4 [plasma membrane] [Homo sapiens]
literatureReference	[LiteratureReference:2272722] Cutting Edge: KIR3DS1, a gene implicated in resistance to progression to AIDS, encodes a DAP12-associated receptor expressed on NK cells that triggers NK cell activation [LiteratureReference:2272770] Detection of KIR3DS1 on the cell surface of peripheral blood NK cells facilitates identification of a novel null allele and assessment of KIR3DS1 expression during HIV-1 infection [LiteratureReference:2272680] KIR/HLA pleiotropism: protection against both HIV and opportunistic infections
modified	[InstanceEdit:2172128] Garapati, P V, 2012-03-28 [InstanceEdit:2272794] Garapati, P V, 2012-05-25 [InstanceEdit:2424475] Garapati, P V, 2012-07-23 [InstanceEdit:2428958] Garapati, P V, 2012-08-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Interaction of DAP12 and KIR3DS1
output	[Complex:2272705] HLA-Bw4:KIR3DS1:DAP12 dimer:KIR3DS1:HLA-Bw4 [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:2130151] Dimerization of DAP12 [Homo sapiens]
releaseDate	2012-09-18
reviewed	[InstanceEdit:2428957] Lanier, Lewis L, 2012-08-09
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2464914] R-HSA-210298.2
summation	[Summation:2272752] Killer cell immunoglobulin-like three-domain short-tail rece...
(hasEvent)	[Pathway:2172127] DAP12 interactions [Homo sapiens]
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No pathways have been reviewed or authored by Interaction of DAP12 and KIR3DS1 (210298)