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Details on Person Recruitment of SYK to p-DAP12

Class:Id	Reaction:210289
_displayName	Recruitment of SYK to p-DAP12
_doRelease	TRUE
_timestamp	2012-09-03 10:22:07
authored	[InstanceEdit:2272794] Garapati, P V, 2012-05-25
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:210296] Garapati, P V, 2008-01-10 13:46:10
edited	[InstanceEdit:2272794] Garapati, P V, 2012-05-25
input	[EntityWithAccessionedSequence:58268] SYK [cytosol] [Homo sapiens] [Complex:2395423] DAP12 receptors:p-Y91,Y102-DAP12 dimer [plasma membrane] [Homo sapiens]
literatureReference	[LiteratureReference:210108] Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells [LiteratureReference:2396584] Functional role for Syk tyrosine kinase in natural killer cell-mediated natural cytotoxicity [LiteratureReference:2396543] DAP12 couples c-Fms activation to the osteoclast cytoskeleton by recruitment of Syk
modified	[InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:2395444] Garapati, P V, 2012-06-29 [InstanceEdit:2395802] Garapati, P V, 2012-07-02 [InstanceEdit:2396616] Garapati, P V, 2012-07-09 [InstanceEdit:2424475] Garapati, P V, 2012-07-23 [InstanceEdit:2428958] Garapati, P V, 2012-08-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Recruitment of SYK to p-DAP12
output	[Complex:210250] DAP12 receptors:p-DAP12:SYK [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:2395439] Phosphorylation of DAP12 [Homo sapiens] [Reaction:2172126] DAP12 interacts with NKG2C [Homo sapiens] [Reaction:210295] Interaction of DAP12 and NKG2D [Homo sapiens] [Reaction:210300] Interaction of DAP12 and TREM2 [Homo sapiens]
releaseDate	2012-09-18
reviewed	[InstanceEdit:2428957] Lanier, Lewis L, 2012-08-09
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2464904] R-HSA-210289.2
summation	[Summation:2395443] Phosphorylated ITAM on DAP12 serves as the docking site for ...
(hasEvent)	[Pathway:2424491] DAP12 signaling [Homo sapiens]
(precedingEvent)	[Reaction:2395412] Phosphorylation of SYK [Homo sapiens]
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No pathways have been reviewed or authored by Recruitment of SYK to p-DAP12 (210289)