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Details on Person Interaction of PECAM-1 and SHP-1

Class:Id	Reaction:210277
_displayName	Interaction of PECAM-1 and SHP-1
_doRelease	TRUE
_timestamp	2009-10-29 14:55:34
authored	[InstanceEdit:214881] de Bono, B, Garapati, P V, 2008-02-26 12:30:30
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:210296] Garapati, P V, 2008-01-10 13:46:10
input	[EntityWithAccessionedSequence:197938] PTPN6 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:210007] p-Y663,Y686-PECAM1(27-?) [plasma membrane] [Homo sapiens]
literatureReference	[LiteratureReference:210035] Recruitment and activation of SHP-1 protein-tyrosine phosphatase by human platelet endothelial cell adhesion molecule-1 (PECAM-1). Identification of immunoreceptor tyrosine-based inhibitory motif-like binding motifs and substrates.
modified	[InstanceEdit:211109] Garapati, P V, 2008-01-28 10:30:53 [InstanceEdit:211549] de Bono, B, 2008-02-06 09:45:07 [InstanceEdit:213345] Gopinathrao, G, 2008-02-25 21:36:16 [InstanceEdit:214779] Garapati, P V, 2008-02-26 12:15:30 [InstanceEdit:214882] Garapati, P V, 2008-02-26 12:32:59 [InstanceEdit:215251] Gopinathrao, G, 2008-02-27 21:37:06 [InstanceEdit:445349] Jupe, S, 2009-10-29 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Interaction of PECAM-1 and SHP-1
output	[Complex:210221] PECAM-1:SHP-1 complex [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:210291] Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src [Homo sapiens] [BlackBoxEvent:435244] PECAM1 is phosphorylated [Homo sapiens]
releaseDate	2008-03-12
reviewed	[InstanceEdit:214481] Trowsdale, J, 2008-02-26 12:02:59
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:358790] R-HSA-210277.2
summation	[Summation:211122] The phosphorylation of two tandem tyrosine residues (Y663 an...
(hasEvent)	[Pathway:210990] PECAM1 interactions [Homo sapiens] [Pathway:432142] Platelet sensitization by LDL [Homo sapiens]
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No pathways have been reviewed or authored by Interaction of PECAM-1 and SHP-1 (210277)