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Details on Person Iodide is taken up by thyroid epithelial cells

Class:IdReaction:209910
_displayNameIodide is taken up by thyroid epithelial cells
_doReleaseTRUE
_timestamp2025-07-28 09:00:52
authored[InstanceEdit:378946] Jassal, Bijay, 2008-10-01
catalystActivity[CatalystActivity:209801] iodide transmembrane transporter activity of SLC5A5 [plasma membrane]
compartment[Compartment:876] plasma membrane
created[InstanceEdit:209970] Jassal, Bijay, 2008-01-08
edited[InstanceEdit:209970] Jassal, Bijay, 2008-01-08
input[SimpleEntity:209818] I- [extracellular region]
[SimpleEntity:74113] Na+ [extracellular region]
[SimpleEntity:74113] Na+ [extracellular region]
literatureReference[LiteratureReference:350105] Cloning of the human sodium lodide symporter
[LiteratureReference:9961626] The Sodium/Iodide Symporter (NIS): Molecular Physiology and Preclinical and Clinical Applications
[LiteratureReference:9961391] The Thyroid Na+/I- Symporter: Molecular Characterization and Genomic Regulation
modified[InstanceEdit:350121] Jassal, Bijay, 2008-05-14
[InstanceEdit:351606] Jassal, B, 2008-05-27 10:37:16
[InstanceEdit:352276] Jassal, Bijay, 2008-06-02
[InstanceEdit:352325] Jassal, Bijay, 2008-06-02
[InstanceEdit:378946] Jassal, Bijay, 2008-10-01
[InstanceEdit:380824] Jassal, Bijay, 2008-11-17
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9961392] Stephan, Ralf, 2025-07-25
[InstanceEdit:9961876] Stephan, Ralf, 2025-07-28
nameIodide is taken up by thyroid epithelial cells
output[SimpleEntity:209785] I- [cytosol]
[SimpleEntity:83910] Na+ [cytosol]
[SimpleEntity:83910] Na+ [cytosol]
releaseDate2008-06-30
reviewed[InstanceEdit:351775] D'Eustachio, P, 2008-05-28 08:30:54
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:387590] R-HSA-209910.3
summation[Summation:209814] Iodide (I-) is transported from blood serum into the thyroid...
(hasEvent)[Pathway:209968] Thyroxine biosynthesis [Homo sapiens]
(updatedInstance)[_UpdateTracker:9964651] Update Tracker - [Reaction:209910] Iodide is taken up by thyroid epithelial cells - v94:[modifyText, removeLiteratureReference]
[_UpdateTracker:9971855] Update Tracker - [Reaction:209910] Iodide is taken up by thyroid epithelial cells - v95:[modifyText]
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