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Details on Person Two DITs combine to form thyroxine

Class:IdReaction:209840
_displayNameTwo DITs combine to form thyroxine
_doReleaseTRUE
_timestamp2010-04-10 18:36:08
authored[InstanceEdit:378946] Jassal, Bijay, 2008-10-01
catalystActivity[CatalystActivity:209956] halogenase activity of p-DUOX1,2:DUOXA1,2:TPO:CAV1:TXNDC11 [plasma membrane]
compartment[Compartment:984] extracellular region
[Compartment:876] plasma membrane
created[InstanceEdit:209970] Jassal, Bijay, 2008-01-08
edited[InstanceEdit:209970] Jassal, Bijay, 2008-01-08
input[SimpleEntity:352329] DIT [extracellular region]
[SimpleEntity:352329] DIT [extracellular region]
literatureReference[LiteratureReference:350844] Biosynthesis of thyroid hormone: basic and clinical aspects
modified[InstanceEdit:350849] Jassal, B, 2008-05-21 10:36:56
[InstanceEdit:352276] Jassal, Bijay, 2008-06-02
[InstanceEdit:352313] Jassal, B, 2008-06-02 10:49:55
[InstanceEdit:352325] Jassal, Bijay, 2008-06-02
[InstanceEdit:378946] Jassal, Bijay, 2008-10-01
[InstanceEdit:380824] Jassal, Bijay, 2008-11-17
[InstanceEdit:576819] D'Eustachio, P, 2010-04-10
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:9606200] Wu, G, 2018-04-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameTwo DITs combine to form thyroxine
output[SimpleEntity:352326] T4 [extracellular region]
[SimpleEntity:352036] L-Ala [extracellular region]
precedingEvent
regulatedBy[PositiveRegulation:1449728] Positive regulation by 'Thyrotropin [extracellular region]'
releaseDate2008-06-30
reviewed[InstanceEdit:351775] D'Eustachio, P, 2008-05-28 08:30:54
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:387693] R-HSA-209840.3
summation[Summation:352311] TPO catalyzes the transfer of a 4-hydroxy-3,5-diiodophenyl m...
(hasEvent)[Pathway:209968] Thyroxine biosynthesis [Homo sapiens]
(precedingEvent)[Reaction:209772] Thyroxine is deiodinated to triiodothyronine [Homo sapiens]
[BlackBoxEvent:9961335] P4HB oligomerizes iodinated TG [Homo sapiens]
[BlackBoxEvent:9966621] TPO oligomerizes iodinated TG [Homo sapiens]
(updatedInstance)[_UpdateTracker:9789472] Update Tracker - [Reaction:209840] Two DITs combine to form thyroxine - v38:[addRegulator, modifyText]
[_UpdateTracker:9790701] Update Tracker - [Reaction:209840] Two DITs combine to form thyroxine - v33:[addOutput]
[_UpdateTracker:9964607] Update Tracker - [Reaction:209840] Two DITs combine to form thyroxine - v94:[modifyText]
[_UpdateTracker:9971881] Update Tracker - [Reaction:209840] Two DITs combine to form thyroxine - v95:[modifyText]
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