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Details on Person Tyrosine hydroxylase (TH) is the first enzyme in catecholami...
| Class:Id | Summation:209781 |
|---|---|
| _displayName | Tyrosine hydroxylase (TH) is the first enzyme in catecholami... |
| _timestamp | 2011-08-02 18:53:35 |
| created | [InstanceEdit:209970] Jassal, Bijay, 2008-01-08 |
| literatureReference | [LiteratureReference:209844] The human tyrosine hydroxylase gene [LiteratureReference:209857] Four isoforms of tyrosine hydroxylase are expressed in human brain [LiteratureReference:350149] Catecholamine biosynthesis and physiological regulation in neuroendocrine cells |
| modified | [InstanceEdit:1470793] Gillespie, ME, 2011-08-02 |
| text | Tyrosine hydroxylase (TH) is the first enzyme in catecholamine biosynthesis, as well as being the rate-limiting enzyme in that process. TH requires tetrahydrobiopterin and uses iron as a cofactor in the 3,4-hydroxylation of tyrosine to produce dopa. Four isoforms of TH are expressed in the human brain and all have enzymatic activity (Nagatsu, T, 1989; Lewis, DA et al, 1993). |
| (summation) | [Reaction:209823] Tyrosine is hydroxylated to dopa [Homo sapiens] |
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No pathways have been reviewed or authored by Tyrosine hydroxylase (TH) is the first enzyme in catecholami... (209781)
